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Challenges and implications of routine depression screening for depression in chronic disease and multimorbidity: a cross sectional study
Depression screening in chronic disease is advocated but its impact on routine practice is uncertain. We examine the effects of a programme of incentivised depression screening in chronic disease within a UK primary care setting. Cross sectional analysis of anonymised, routinely collected data (2008...
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Published in: | PloS one 2013-09, Vol.8 (9), p.e74610-e74610 |
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description | Depression screening in chronic disease is advocated but its impact on routine practice is uncertain. We examine the effects of a programme of incentivised depression screening in chronic disease within a UK primary care setting.
Cross sectional analysis of anonymised, routinely collected data (2008-9) from family practices in Scotland serving a population of circa 1.8 million. Primary care registered patients with at least one of three chronic diseases, coronary heart disease, diabetes and stroke, underwent incentivised depression screening using the Hospital Anxiety and Depression Score (HADS). 125143 patients were identified with at least one chronic disease. 10670 (8.5%) were under treatment for depression and exempt from screening. Of remaining, HADS were recorded for 35537 (31.1%) patients. 7080 (19.9% of screened) had raised HADS (≥8); majority had indications of mild depression with HADS between 8 and 10. Over 6 months, 572 (8%) of those with raised HADS (≥8) were initiated on antidepressants, while 696 (2.4%) patients with normal HADS ( |
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Cross sectional analysis of anonymised, routinely collected data (2008-9) from family practices in Scotland serving a population of circa 1.8 million. Primary care registered patients with at least one of three chronic diseases, coronary heart disease, diabetes and stroke, underwent incentivised depression screening using the Hospital Anxiety and Depression Score (HADS). 125143 patients were identified with at least one chronic disease. 10670 (8.5%) were under treatment for depression and exempt from screening. Of remaining, HADS were recorded for 35537 (31.1%) patients. 7080 (19.9% of screened) had raised HADS (≥8); majority had indications of mild depression with HADS between 8 and 10. Over 6 months, 572 (8%) of those with raised HADS (≥8) were initiated on antidepressants, while 696 (2.4%) patients with normal HADS (<8) were also initiated on antidepressants (relative risk of antidepressant initiation with raised HADS 3.3 (CI 2.97-3.67), p value <0.0001). Of those with multimorbidity who were screened, 24.3% had raised HADS (≥8). A raised HADS was more likely in females, socioeconomically deprived, multimorbid or younger (18-44) individuals. Females and 45-64 years old were more likely to receive antidepressants.
retrospective study of routinely collected data.
Despite incentivisation, only a minority of patients underwent depression screening, suggesting that systematic depression screening in chronic disease can be difficult to achieve in routine practice. Targeting those at greatest risk such as the multimorbid or using simpler screening methods may be more effective. Raised HADS was associated with higher number of new antidepressant prescriptions which has significant resource implications. The clinical benefits of such screening remain uncertain and merits investigation.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0074610</identifier><identifier>PMID: 24058602</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Activities of daily living ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aging - pathology ; Analysis ; Antidepressants ; Antidepressive Agents - therapeutic use ; Anxiety ; Cardiovascular disease ; Cardiovascular diseases ; Chronic Disease ; Chronic diseases ; Chronic illnesses ; Clinical outcomes ; Comorbidity ; Coronary artery disease ; Coronary heart disease ; Cross-Sectional Studies ; Demography ; Depression (Mood disorder) ; Depression - diagnosis ; Depression - drug therapy ; Depression - epidemiology ; Diabetes ; Diabetes mellitus ; Ethics ; Family medicine ; Female ; Females ; Health care ; Health screening ; Heart diseases ; Humans ; Male ; Mass Screening ; Medical diagnosis ; Medical research ; Medical screening ; Medical treatment ; Mental depression ; Mental health ; Middle Aged ; Multimorbidity ; Patient compliance ; Patients ; Pay for performance ; Population ; Practice Patterns, Physicians ; Primary care ; Regression Analysis ; Stroke ; Studies ; Time Factors ; Tricyclic antidepressants ; United Kingdom - epidemiology ; Young Adult</subject><ispartof>PloS one, 2013-09, Vol.8 (9), p.e74610-e74610</ispartof><rights>COPYRIGHT 2013 Public Library of Science</rights><rights>2013 Jani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2013 Jani et al 2013 Jani et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-939919e1a4369bb70c1ead9ac145e5f3bbebbe846f566986720f36d359d5b8ea3</citedby><cites>FETCH-LOGICAL-c692t-939919e1a4369bb70c1ead9ac145e5f3bbebbe846f566986720f36d359d5b8ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1432296830/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1432296830?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24058602$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Bayer, Antony</contributor><creatorcontrib>Jani, Bhautesh Dinesh</creatorcontrib><creatorcontrib>Purves, David</creatorcontrib><creatorcontrib>Barry, Sarah</creatorcontrib><creatorcontrib>Cavanagh, Jonathan</creatorcontrib><creatorcontrib>McLean, Gary</creatorcontrib><creatorcontrib>Mair, Frances S</creatorcontrib><title>Challenges and implications of routine depression screening for depression in chronic disease and multimorbidity: a cross sectional study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Depression screening in chronic disease is advocated but its impact on routine practice is uncertain. We examine the effects of a programme of incentivised depression screening in chronic disease within a UK primary care setting.
Cross sectional analysis of anonymised, routinely collected data (2008-9) from family practices in Scotland serving a population of circa 1.8 million. Primary care registered patients with at least one of three chronic diseases, coronary heart disease, diabetes and stroke, underwent incentivised depression screening using the Hospital Anxiety and Depression Score (HADS). 125143 patients were identified with at least one chronic disease. 10670 (8.5%) were under treatment for depression and exempt from screening. Of remaining, HADS were recorded for 35537 (31.1%) patients. 7080 (19.9% of screened) had raised HADS (≥8); majority had indications of mild depression with HADS between 8 and 10. Over 6 months, 572 (8%) of those with raised HADS (≥8) were initiated on antidepressants, while 696 (2.4%) patients with normal HADS (<8) were also initiated on antidepressants (relative risk of antidepressant initiation with raised HADS 3.3 (CI 2.97-3.67), p value <0.0001). Of those with multimorbidity who were screened, 24.3% had raised HADS (≥8). A raised HADS was more likely in females, socioeconomically deprived, multimorbid or younger (18-44) individuals. Females and 45-64 years old were more likely to receive antidepressants.
retrospective study of routinely collected data.
Despite incentivisation, only a minority of patients underwent depression screening, suggesting that systematic depression screening in chronic disease can be difficult to achieve in routine practice. Targeting those at greatest risk such as the multimorbid or using simpler screening methods may be more effective. Raised HADS was associated with higher number of new antidepressant prescriptions which has significant resource implications. The clinical benefits of such screening remain uncertain and merits investigation.</description><subject>Activities of daily living</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging - pathology</subject><subject>Analysis</subject><subject>Antidepressants</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Anxiety</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Chronic Disease</subject><subject>Chronic diseases</subject><subject>Chronic illnesses</subject><subject>Clinical outcomes</subject><subject>Comorbidity</subject><subject>Coronary artery disease</subject><subject>Coronary heart disease</subject><subject>Cross-Sectional Studies</subject><subject>Demography</subject><subject>Depression (Mood disorder)</subject><subject>Depression - diagnosis</subject><subject>Depression - drug therapy</subject><subject>Depression - epidemiology</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Ethics</subject><subject>Family medicine</subject><subject>Female</subject><subject>Females</subject><subject>Health care</subject><subject>Health screening</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Medical diagnosis</subject><subject>Medical research</subject><subject>Medical screening</subject><subject>Medical treatment</subject><subject>Mental depression</subject><subject>Mental health</subject><subject>Middle Aged</subject><subject>Multimorbidity</subject><subject>Patient compliance</subject><subject>Patients</subject><subject>Pay for performance</subject><subject>Population</subject><subject>Practice Patterns, Physicians</subject><subject>Primary care</subject><subject>Regression Analysis</subject><subject>Stroke</subject><subject>Studies</subject><subject>Time Factors</subject><subject>Tricyclic antidepressants</subject><subject>United Kingdom - 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pathology</topic><topic>Analysis</topic><topic>Antidepressants</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Anxiety</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Chronic Disease</topic><topic>Chronic diseases</topic><topic>Chronic illnesses</topic><topic>Clinical outcomes</topic><topic>Comorbidity</topic><topic>Coronary artery disease</topic><topic>Coronary heart disease</topic><topic>Cross-Sectional Studies</topic><topic>Demography</topic><topic>Depression (Mood disorder)</topic><topic>Depression - diagnosis</topic><topic>Depression - drug therapy</topic><topic>Depression - epidemiology</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Ethics</topic><topic>Family medicine</topic><topic>Female</topic><topic>Females</topic><topic>Health care</topic><topic>Health screening</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Male</topic><topic>Mass Screening</topic><topic>Medical diagnosis</topic><topic>Medical research</topic><topic>Medical screening</topic><topic>Medical treatment</topic><topic>Mental depression</topic><topic>Mental health</topic><topic>Middle Aged</topic><topic>Multimorbidity</topic><topic>Patient compliance</topic><topic>Patients</topic><topic>Pay for performance</topic><topic>Population</topic><topic>Practice Patterns, Physicians</topic><topic>Primary care</topic><topic>Regression Analysis</topic><topic>Stroke</topic><topic>Studies</topic><topic>Time Factors</topic><topic>Tricyclic antidepressants</topic><topic>United Kingdom - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jani, Bhautesh Dinesh</au><au>Purves, David</au><au>Barry, Sarah</au><au>Cavanagh, Jonathan</au><au>McLean, Gary</au><au>Mair, Frances S</au><au>Bayer, Antony</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Challenges and implications of routine depression screening for depression in chronic disease and multimorbidity: a cross sectional study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2013-09-13</date><risdate>2013</risdate><volume>8</volume><issue>9</issue><spage>e74610</spage><epage>e74610</epage><pages>e74610-e74610</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Depression screening in chronic disease is advocated but its impact on routine practice is uncertain. We examine the effects of a programme of incentivised depression screening in chronic disease within a UK primary care setting.
Cross sectional analysis of anonymised, routinely collected data (2008-9) from family practices in Scotland serving a population of circa 1.8 million. Primary care registered patients with at least one of three chronic diseases, coronary heart disease, diabetes and stroke, underwent incentivised depression screening using the Hospital Anxiety and Depression Score (HADS). 125143 patients were identified with at least one chronic disease. 10670 (8.5%) were under treatment for depression and exempt from screening. Of remaining, HADS were recorded for 35537 (31.1%) patients. 7080 (19.9% of screened) had raised HADS (≥8); majority had indications of mild depression with HADS between 8 and 10. Over 6 months, 572 (8%) of those with raised HADS (≥8) were initiated on antidepressants, while 696 (2.4%) patients with normal HADS (<8) were also initiated on antidepressants (relative risk of antidepressant initiation with raised HADS 3.3 (CI 2.97-3.67), p value <0.0001). Of those with multimorbidity who were screened, 24.3% had raised HADS (≥8). A raised HADS was more likely in females, socioeconomically deprived, multimorbid or younger (18-44) individuals. Females and 45-64 years old were more likely to receive antidepressants.
retrospective study of routinely collected data.
Despite incentivisation, only a minority of patients underwent depression screening, suggesting that systematic depression screening in chronic disease can be difficult to achieve in routine practice. Targeting those at greatest risk such as the multimorbid or using simpler screening methods may be more effective. Raised HADS was associated with higher number of new antidepressant prescriptions which has significant resource implications. The clinical benefits of such screening remain uncertain and merits investigation.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>24058602</pmid><doi>10.1371/journal.pone.0074610</doi><tpages>e74610</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Activities of daily living Adolescent Adult Aged Aged, 80 and over Aging - pathology Analysis Antidepressants Antidepressive Agents - therapeutic use Anxiety Cardiovascular disease Cardiovascular diseases Chronic Disease Chronic diseases Chronic illnesses Clinical outcomes Comorbidity Coronary artery disease Coronary heart disease Cross-Sectional Studies Demography Depression (Mood disorder) Depression - diagnosis Depression - drug therapy Depression - epidemiology Diabetes Diabetes mellitus Ethics Family medicine Female Females Health care Health screening Heart diseases Humans Male Mass Screening Medical diagnosis Medical research Medical screening Medical treatment Mental depression Mental health Middle Aged Multimorbidity Patient compliance Patients Pay for performance Population Practice Patterns, Physicians Primary care Regression Analysis Stroke Studies Time Factors Tricyclic antidepressants United Kingdom - epidemiology Young Adult |
title | Challenges and implications of routine depression screening for depression in chronic disease and multimorbidity: a cross sectional study |
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