Assessment of the rotation motion at the papillary muscle short-axis plane with normal subjects by two-dimensional speckle tracking imaging: a basic clinical study

• Published in: PloS one 2013-12, Vol.8 (12), p.e83071-e83071
• Main Authors: Ni, Xian-Da, Huang, Jun, Hu, Yuan-Ping, Xu, Rui, Yang, Wei-Yu, Zhou, Li-Ming
• Format: Article
• Language: English
• Subjects: Adult; Age; Aircraft; Biomechanics; Cardiomyopathy; Clinical trials; Echocardiography - methods; Electrocardiography; Female; Heart; Heart rate; Heart Ventricles - diagnostic imaging; Human subjects; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Muscles; Myocardial Contraction - physiology; Papillary Muscles - diagnostic imaging; Papillary Muscles - physiology; ROC Curve; Rotation; Stroke Volume - physiology; Three dimensional motion; Torsion; Tracking; Velocity; Ventricle; Ventricular Function, Left
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0083071

The aim of this study was to observe the rotation patterns at the papillary muscle plane in the Left Ventricle(LV) with normal subjects using two-dimensional speckle tracking imaging(2D-STI). We acquired standard of the basal, the papillary muscle and the apical short-axis images of the LV in 64 subjects to estimate the LV rotation motion by 2D-STI. The rotational degrees at the papillary muscle short-axis plane were measured at 15 different time points in the analysis of two heart cycles. There were counterclockwise rotation, clockwise rotation, and counterclockwise to clockwise rotation at the papillary muscle plane in the LV with normal subjects, respectively. The ROC analysis of the rotational degrees was performed at the papillary muscle short-axis plane at the peak LV torsion for predicting whether the turnaround point of twist to untwist motion pattern was located at the papillary muscle level. Sensitivity and specificity were 97% and 67%, respectively, with a cut-off value of 0.34°, and an area under the ROC curve of 0.8. At the peak LV torsion, there was no correlation between the rotational degrees at the papillary muscle short-axis plane and the LVEF in the normal subjects(r = 0.000, p = 0.998). In the study, we conclude that there were three rotation patterns at the papillary muscle short-axis levels, and the transition from basal clockwise rotation to apical counterclockwise rotation is located at the papillary muscle level.