Venezuelan equine encephalitis viruses (VEEV) in Argentina: serological evidence of human infection

Venezuelan equine encephalitis viruses (VEEV) are responsible for human diseases in the Americas, producing severe or mild illness with symptoms indistinguishable from dengue and other arboviral diseases. For this reason, many cases remain without certain diagnosis. Seroprevalence studies for VEEV s...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2013-12, Vol.7 (12), p.e2551-e2551
Main Authors: Pisano, María Belén, Oria, Griselda, Beskow, Geraldine, Aguilar, Javier, Konigheim, Brenda, Cacace, María Luisa, Aguirre, Luis, Stein, Marina, Contigiani, Marta Silvia
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antibodies, Neutralizing - blood
Antibodies, Viral - blood
Argentina - epidemiology
Child, Preschool
Disease
Distribution
Encephalitis
Encephalitis Virus, Venezuelan Equine - immunology
Encephalitis, Viral
Encephalomyelitis, Venezuelan Equine - epidemiology
Female
Hospitals
Host-parasite relationships
Humans
Illnesses
Male
Microbiological research
Middle Aged
Mosquitoes
Neutralization Tests
Pediatrics
Pixuna virus
Prevalence studies (Epidemiology)
Provinces
Seroepidemiologic Studies
Studies
Viruses
Young Adult
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Description
Summary:Venezuelan equine encephalitis viruses (VEEV) are responsible for human diseases in the Americas, producing severe or mild illness with symptoms indistinguishable from dengue and other arboviral diseases. For this reason, many cases remain without certain diagnosis. Seroprevalence studies for VEEV subtypes IAB, ID, IF (Mosso das Pedras virus; MDPV), IV (Pixuna virus; PIXV) and VI (Rio Negro virus; RNV) were conducted in persons from Northern provinces of Argentina: Salta, Chaco and Corrientes, using plaque reduction neutralization test (PRNT). RNV was detected in all studied provinces. Chaco presented the highest prevalence of this virus (14.1%). Antibodies against VEEV IAB and -for the first time- against MDPV and PIXV were also detected in Chaco province. In Corrientes, seroprevalence against RNV was 1.3% in the pediatric population, indicating recent infections. In Salta, this was the first investigation of VEEV members, and antibodies against RNV and PIXV were detected. These results provide evidence of circulation of many VEE viruses in Northern Argentina, showing that surveillance of these infectious agents should be intensified.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0002551