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Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women

Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phth...

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Published in:PloS one 2014-02, Vol.9 (2), p.e87430-e87430
Main Authors: Huang, Yujing, Li, Junnan, Garcia, Jose M, Lin, Hui, Wang, Yanzhou, Yan, Ping, Wang, Lingqiao, Tan, Yao, Luo, Jiaohua, Qiu, Zhiqun, Chen, Ji-an, Shu, Weiqun
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description Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phthalates except DCHP was associated with gestational age reduction and preterm delivery (p
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In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phthalates except DCHP was associated with gestational age reduction and preterm delivery (p&lt;0.05). There were associations between phthalates and fetal growth parameters, many of which disappeared when analyses were adjusted for gestational age, especially in male infants (Only DEEP was associated with birth weight; DEP, DNHP, BBP, DNP with abdominal circumference; DEP, DBP, DCHP, DEHP with femur length in female infants. And DPP, DBEP was associated with birth length in male infants. p&lt;0.05). This study indicates that prenatal exposure to phthalates is associated with younger gestational age and preterm delivery. 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subjects Age
Asian Continental Ancestry Group
Biology
Birth Weight
Blood
Breastfeeding & lactation
China
Consent
Cord blood
Endocrinology
Environmental health
Esters
Esters - blood
Exposure
Family medical history
Female
Femur
Fetal Blood - metabolism
Fetal Development
Fetuses
Gallbladder diseases
Gestational Age
Growth
Gynecology
Hospitals
Humans
Hygiene
Infant, Newborn
Infants
Inflammatory diseases
Male
Medicine
Metabolites
Molecular weight
Obstetrics
Phthalate plasticizers
Phthalates
Phthalic Acids - blood
Pregnancy
Pregnancy complications
Pregnant Women
Premature birth
Premature Birth - blood
Prenatal experience
Prenatal exposure
Preventive medicine
Reduction
Rodents
Studies
Urine
Womens health
title Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women
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