Preclinical screening for retinopathy of prematurity risk using IGF1 levels at 3 weeks post-partum

Following current recommendations for preventing retinopathy of prematurity (ROP) involves screening a large number of patients. We performed a prospective study to establish a useful screening system for ROP prediction and we have determined that measuring serum levels of IGF1 at week three and the...

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Bibliographic Details
Published in:PloS one 2014-02, Vol.9 (2), p.e88781-e88781
Main Authors: Pérez-Muñuzuri, Alejandro, Couce-Pico, Maria Luz, Baña-Souto, Ana, López-Suárez, Olalla, Iglesias-Deus, Alicia, Blanco-Teijeiro, José, Fernández-Lorenzo, José Ramón, Fraga-Bermúdez, José María
Format: Article
Language:English
Subjects:
Age
Babies
Biology
Birth Weight
Cryotherapy
Dysplasia
Erythrocytes
Erythropoietin
Female
Gestational Age
Hemorrhage
Humans
Infant, Newborn
Infection
Insulin
Insulin-like growth factor I
Insulin-Like Growth Factor I - analysis
Insulin-like growth factors
Male
Mechanical ventilation
Medical research
Medical screening
Medicine
Neonatal Screening - methods
Newborn babies
Ophthalmology
Oxygen
Oxygen - chemistry
Patients
Pediatrics
Predictions
Predictive Value of Tests
Premature birth
Prospective Studies
Red blood cells
Regression Analysis
Respiration, Artificial
Retina
Retinopathy
Retinopathy of prematurity
Retinopathy of Prematurity - blood
Retinopathy of Prematurity - diagnosis
Risk Factors
Screening
Sepsis
Sepsis - blood
Serum levels
Statistical analysis
Transfusion
Ventilation
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Summary:Following current recommendations for preventing retinopathy of prematurity (ROP) involves screening a large number of patients. We performed a prospective study to establish a useful screening system for ROP prediction and we have determined that measuring serum levels of IGF1 at week three and the presence of sepsis have a high predictive value for the subsequent development of ROP. A total of 145 premature newborn, with birthweight
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0088781