Molecular diagnostics for gonorrhoea: implications for antimicrobial resistance and the threat of untreatable gonorrhoea

This Essay from Nicola Low and colleagues discusses the importance of the nucleic acid amplification tests for rapid detection of N. gonorrhoeae and its resistance determinants, as well as the importance of ensuring their rational use, as priorities for controlling both gonorrhoea and antimicrobial...

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Bibliographic Details
Published in:PLoS medicine 2014-02, Vol.11 (2), p.e1001598-e1001598
Main Authors: Low, Nicola, Unemo, Magnus, Skov Jensen, Jørgen, Breuer, Judith, Stephenson, Judith M
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Antimicrobial agents
Care and treatment
Causes of
Complications and side effects
Diagnosis
DNA, Bacterial - isolation & purification
Drug resistance
Drug resistance in microorganisms
Drug Resistance, Bacterial - genetics
Genetic aspects
Gonorrhea
Gonorrhea - diagnosis
Gonorrhea - drug therapy
Gonorrhea - microbiology
Health services
Humans
Medicine
Mens health
Microbial Sensitivity Tests
Molecular Diagnostic Techniques
Mutation
Neisseria gonorrhoeae - drug effects
Neisseria gonorrhoeae - genetics
Neisseria gonorrhoeae - growth & development
Neisseria gonorrhoeae - isolation & purification
Nucleic Acid Amplification Techniques
Polymerase chain reaction
Precision Medicine
Predictive Value of Tests
Public health
Sexually transmitted diseases
Staphylococcus infections
STD
Treatment Failure
Tuberculosis
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Summary:This Essay from Nicola Low and colleagues discusses the importance of the nucleic acid amplification tests for rapid detection of N. gonorrhoeae and its resistance determinants, as well as the importance of ensuring their rational use, as priorities for controlling both gonorrhoea and antimicrobial resistance. Please see later in the article for the Editors' Summary
ISSN:1549-1676
1549-1277
1549-1676
DOI:10.1371/journal.pmed.1001598