Identification of direct and indirect social network effects in the pathophysiology of insulin resistance in obese human subjects

The aim of the present study was to examine to what extent different social network mechanisms are involved in the pathogenesis of obesity and insulin-resistance. We used nonparametric and parametric regression models to analyse whether individual BMI and HOMA-IR are determined by social network cha...

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Bibliographic Details
Published in:PloS one 2014-04, Vol.9 (4), p.e93860
Main Authors: Henning, Christian H C A, Zarnekow, Nana, Hedtrich, Johannes, Stark, Sascha, Türk, Kathrin, Laudes, Matthias
Format: Article
Language:English
Subjects:
Adult
Aged
Anthropometry
Biology and Life Sciences
Body mass
Body Mass Index
Brain
Care and treatment
Complications and side effects
Computer and Information Sciences
Cross-Sectional Studies
Diabetes mellitus
Female
Health
Health Status
Human behavior
Humans
Insulin
Insulin resistance
Insulin Resistance - physiology
Male
Medicine and Health Sciences
Middle Aged
Obesity
Obesity - physiopathology
Obesity - psychology
Pathogenesis
Patient outcomes
Peer Group
Physical Sciences
Regression analysis
Regression models
Research and Analysis Methods
Risk factors
Social factors
Social networks
Social organization
Social Sciences
Social Support
Studies
Type 2 diabetes
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Summary:The aim of the present study was to examine to what extent different social network mechanisms are involved in the pathogenesis of obesity and insulin-resistance. We used nonparametric and parametric regression models to analyse whether individual BMI and HOMA-IR are determined by social network characteristics. A total of 677 probands (EGO) and 3033 social network partners (ALTER) were included in the study. Data gathered from the probands include anthropometric measures, HOMA-IR index, health attitudes, behavioural and socio-economic variables and social network data. We found significant treatment effects for ALTERs frequent dieting (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0093860