Genotypes of Enterocytozoon bieneusi in livestock in China: high prevalence and zoonotic potential

Despite many recent advances in genotype characterization of Enterocytozoon bieneusi worldwide and the exploration of the extent of cross-species transmission of microsporidiosis between humans and animals, the epidemiology of this neglected disease in China is poorly understood. In this study, a ve...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2014-05, Vol.9 (5), p.e97623-e97623
Main Authors: Li, Wei, Li, Yijing, Li, Weizhi, Yang, Jinping, Song, Mingxin, Diao, Ruinan, Jia, Honglin, Lu, Yixin, Zheng, Jun, Zhang, Xichen, Xiao, Lihua
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Animals
Biology and Life Sciences
China
Deoxyribonucleic acid
DNA
DNA sequencing
Enterocytozoon - genetics
Enterocytozoon bieneusi
Epidemiology
Female
Genetic aspects
Genotype
Genotypes
HIV
Human immunodeficiency virus
Humans
Infection
Infections
Livestock
Male
Microsporidiosis
Microsporidiosis - epidemiology
Microsporidiosis - genetics
Microsporidiosis - veterinary
Nucleotide sequence
Ovis aries
Pigs
Pork industry
Prevalence
Prevalence studies (Epidemiology)
Sheep
Sheep Diseases - epidemiology
Sheep Diseases - genetics
Sheep Diseases - microbiology
Spacer
Suidae
Swine
Swine Diseases - epidemiology
Swine Diseases - genetics
Swine Diseases - microbiology
Veterinary colleges
Wastewater
Weaning
Zoonoses
Zoonoses - epidemiology
Zoonoses - genetics
Zoonoses - microbiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Despite many recent advances in genotype characterization of Enterocytozoon bieneusi worldwide and the exploration of the extent of cross-species transmission of microsporidiosis between humans and animals, the epidemiology of this neglected disease in China is poorly understood. In this study, a very high prevalence (60.3%; 94/156) of E. bieneusi infections in farmed pigs in Jilin province was detected by PCR of the ribosomal internal transcribed spacer (ITS). DNA sequence analysis of 88 E. bieneusi-positive specimens identified 12 distinct genotypes (11 known: CHN7, CS-1, CS-4, CS-6, EbpA, EbpB, EbpC, EbpD, EBITS3, G, and Henan-I; one novel: CS-9). Frequent appearance of mixed genotype infections was seen in the study animals. Weaned (74.6%; 53/71) or pre-weaned (68.8%; 22/32) pigs have infection rates significantly higher than growing pigs (35.8%; 19/53) (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0097623