Relationship between lifetime suicide attempts and schizotypal traits in patients with schizophrenia

• Published in: PloS one 2014-09, Vol.9 (9), p.e107739-e107739
• Main Authors: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ishida, Ikki, Nagashima, Anna, Kinoshita, Yukiko, Ota, Miho, Hattori, Kotaro, Kunugi, Hiroshi
• Format: Article
• Language: English
• Subjects: Adult; Age; Antipsychotics; Biology and Life Sciences; Bipolar disorder; Case-Control Studies; Cognitive ability; Confidence intervals; Covariance; Female; Humans; Male; Males; Medicine and Health Sciences; Mental disorders; Middle Aged; Mortality; Odds Ratio; Patients; Personality; Personality Assessment; Psychometrics; Quantitative Trait, Heritable; Risk analysis; Risk assessment; Risk factors; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - drug therapy; Schizophrenia - epidemiology; Schizophrenic Psychology; Self destructive behavior; Social Sciences; Suicide; Suicide, Attempted - psychology; Suicides & suicide attempts; Surveys and Questionnaires
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0107739

Patients with schizophrenia are at increased risk for suicide. Various risk factors for suicide have been reported in schizophrenia; however, few studies have examined the association between personality traits and suicidal behavior. We administered the Schizotypal Personality Questionnaire (SPQ) to 87 Japanese patients with schizophrenia (49 males; mean age 38.1 ± 10.6 years) with and without a history of suicide attempts (SA and nSA groups, respectively), and 322 controls (158 males; mean age 40.8 ± 13.9 years). As expected, an analysis of covariance (ANCOVA) controlling for age and sex showed that all SPQ indices (total SPQ score and all three factors, i.e., cognitive-perceptual, interpersonal, and disorganized) were significantly higher in patients with schizophrenia (SA+nSA groups), than controls (p