Impact of conjunctivochalasis on visual quality of life: a community population survey

• Published in: PloS one 2014-10, Vol.9 (10), p.e110821-e110821
• Main Authors: Le, Qihua, Cui, Xinhan, Xiang, Jun, Ge, Ling, Gong, Lan, Xu, Jianjiang
• Format: Article
• Language: English
• Subjects: Abnormalities; Adult; Aged; Aged, 80 and over; China - epidemiology; Comparative analysis; Comparative studies; Conjunctival Diseases - epidemiology; Conjunctival Diseases - pathology; Conjunctival Diseases - physiopathology; Cornea; Correlation; Correlation analysis; Cross-Sectional Studies; Dry Eye Syndromes - epidemiology; Dry Eye Syndromes - pathology; Dry Eye Syndromes - physiopathology; Eye; Eye diseases; Female; Health aspects; Hospitals; Humans; Laboratories; Male; Medicine and Health Sciences; Meniscus; Middle Aged; Myopia; Occlusion; Pathogenesis; Patients; Population; Quality of Life; Questionnaires; Severity of Illness Index; Sociodemographics; Subgroups; Surveys; Surveys and Questionnaires; Tearing; Tomography; Vision, Ocular
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0110821

Conjunctivochalasis (Cch) is a very common ocular disorder, which can cause an unstable tear film and ocular discomfort. The study of vision-related quality of life (VR-QoL) in a community population with Cch can provide a better understanding of the impact of Cch on common people than objective clinical examinations alone. This cross-sectional comparative study enrolled 360 participants ≥ 40 years old living in Sanle Community, Shanghai. In the study, 198 subjects were diagnosed with Cch and 86 with dry eye syndrome (DES) without Cch. The remaining 76 subjects were normal controls. Socio-demographical data were collected, and Cch and related ocular symptoms and signs were evaluated. In addition, all participants were required to complete the Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) and Ocular Surface Disease Index Questionnaire (OSDI). Main outcome measures include the comparison on the OSDI score and VFQ-25 score among the subgroups, and the correlation of these scores with the socio-demographical and clinical data. The results revealed that subjects with Cch had significantly decreased tear film stability even compared with those with DES (P = 0.001). The participants with either Cch or DES reported significantly higher OSDI scores and lower VFQ-25 composite scores than the normal controls (P