The effects of lifestyle interventions on (long-term) weight management, cardiometabolic risk and depressive symptoms in people with psychotic disorders: a meta-analysis

The aim of this study was to estimate the effects of lifestyle interventions on bodyweight and other cardiometabolic risk factors in people with psychotic disorders. Additionally, the long-term effects on body weight and the effects on depressive symptoms were examined. We searched four databases fo...

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Bibliographic Details
Published in:PloS one 2014-12, Vol.9 (12), p.e112276-e112276
Main Authors: Bruins, Jojanneke, Jörg, Frederike, Bruggeman, Richard, Slooff, Cees, Corpeleijn, Eva, Pijnenborg, Marieke
Format: Article
Language:English
Subjects:
Behavior disorders
Biology and Life Sciences
Blood pressure
Blood Pressure - physiology
Body Mass Index
Body Weight
Body weight gain
Body weight loss
Cardiovascular disease
Cholesterol
Clinical trials
Comparative analysis
Depression (Mood disorder)
Depression - complications
Depression - epidemiology
Diabetes
Disorders
Exercise
Glucose
Health risks
Humans
Insulin
Insulin Resistance - physiology
Intervention
Life Style
Lifestyles
Long-term effects
Medicine and Health Sciences
Mental depression
Mental disorders
Meta-analysis
Metabolic syndrome
Mortality
Nutrition research
Obesity
Obesity - complications
Obesity - epidemiology
Patients
Physical fitness
Population
Prevention
Psychiatry
Psychosis
Psychotherapy
Psychotic disorders
Psychotic Disorders - complications
Psychotic Disorders - epidemiology
Psychotropic drugs
Research and Analysis Methods
Risk analysis
Risk Factors
Risk management
Studies
Substance abuse treatment
Triglycerides
Weight control
Weight Loss
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Summary:The aim of this study was to estimate the effects of lifestyle interventions on bodyweight and other cardiometabolic risk factors in people with psychotic disorders. Additionally, the long-term effects on body weight and the effects on depressive symptoms were examined. We searched four databases for randomized controlled trials (RCTs) that compared lifestyle interventions to control conditions in patients with psychotic disorders. Lifestyle interventions were aimed at weight loss or weight gain prevention, and the study outcomes included bodyweight or metabolic parameters. The search resulted in 25 RCTs -only 4 were considered high quality- showing an overall effect of lifestyle interventions on bodyweight (effect size (ES)  =  -0.63, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0112276