Axial length/corneal radius ratio: association with refractive state and role on myopia detection combined with visual acuity in Chinese schoolchildren

To evaluate the association between the AL/CR ratio and refractive state and explore the effectiveness of this ratio in the assessment of myopia, especially when combined with uncorrected visual acuity in schoolchildren among whom myopia is common. Cross sectional study. 4686 children from 6 primary...

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Bibliographic Details
Published in:PloS one 2015-02, Vol.10 (2), p.e0111766-e0111766
Main Authors: He, Xiangui, Zou, Haidong, Lu, Lina, Zhao, Rong, Zhao, Huijuan, Li, Qiangqiang, Zhu, Jianfeng
Format: Article
Language:English
Subjects:
Acuity
Analysis
Asian Continental Ancestry Group
Astigmatism
Child
Children
China - epidemiology
Cornea
Cornea - anatomy & histology
Cornea - pathology
Cross-Sectional Studies
Disease prevention
Elementary school students
Eye diseases
Female
Hospitals
Humans
Male
Medical referrals
Myopia
Myopia - diagnosis
Myopia - epidemiology
Optometry
Prevalence
Public health
Radius of curvature
Random sampling
Refraction
Refraction, Ocular
Regression analysis
Regression models
ROC Curve
Sampling methods
Sensitivity
Statistical analysis
Statistical sampling
Systematic review
Vision Tests
Visual Acuity
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Summary:To evaluate the association between the AL/CR ratio and refractive state and explore the effectiveness of this ratio in the assessment of myopia, especially when combined with uncorrected visual acuity in schoolchildren among whom myopia is common. Cross sectional study. 4686 children from 6 primary schools, aged from 6 to 12 years were selected using the clustered-stratified random sampling method. Uncorrected visual acuity (UCVA), axial length (AL), corneal radius of curvature (CR), and cycloplegic refraction were tested. Refraction was measured as the spherical equivalent (SE). 3922 children were included in the analysis. The mean AL/CR ratio was 2.973±0.002, increased with age, and different in gender. The coefficients of correlations of the SE with the AL/CR ratio, AL, and CR were -0.811, -0.657, and 0.095, respectively. Linear regression showed a 10.72 D shift towards myopia with every 1 unit increase in the AL/CR ratio (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0111766