Comparison of discectomy versus sequestrectomy in lumbar disc herniation: a meta-analysis of comparative studies

Lumbar disc removal is currently the standard treatment for lumbar disc herniation. No consensus has been achieved whether aggressive disc resection with curettage (discectomy) versus conservative removal of the offending disc fragment alone (sequestrectomy) provides better outcomes. This study aims...

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Bibliographic Details
Published in:PloS one 2015-03, Vol.10 (3), p.e0121816-e0121816
Main Authors: Ran, Jisheng, Hu, Yejun, Zheng, Zefeng, Zhu, Ting, Zheng, Huawei, Jing, Yibiao, Xu, Kan
Format: Article
Language:English
Subjects:
Analgesics
Back pain
Bone surgery
Clinical outcomes
Clinical trials
Comparative analysis
Comparative studies
Complications
Curettage
Demographic variables
Demographics
Diskectomy - adverse effects
Diskectomy - methods
Female
Hospitals
Humans
Intervertebral Disc Displacement - surgery
Intervertebral discs
Length of Stay
Literature reviews
Low back pain
Lumbar Vertebrae - surgery
Male
Mathematical analysis
Medicine
Meta-analysis
Microsurgery - adverse effects
Microsurgery - methods
Neurosurgery
Orthopedics
Pain
Pain, Postoperative - diagnosis
Pain, Postoperative - etiology
Patient Satisfaction
Population
Quality
Randomization
Recurrence
Sciatica
Spinal manipulation
Studies
Systematic review
Treatment Outcome
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Summary:Lumbar disc removal is currently the standard treatment for lumbar disc herniation. No consensus has been achieved whether aggressive disc resection with curettage (discectomy) versus conservative removal of the offending disc fragment alone (sequestrectomy) provides better outcomes. This study aims to compare the reherniation rate and clinical outcomes between discectomy and sequestrectomy by literature review and a meta-analysis. A systematic search of PubMed, Medline, Embase and the Cochrane Library was performed up to June 1, 2014. Outcomes of interest assessing the two techniques included demographic and clinical baseline characteristics, perioperative variables, complications, recurrent herniation rate and post-operative functional outcomes. Twelve eligible trials evaluating discectomy vs sequestrectomy were identified including one randomized controlled study, five prospective and six retrospective comparative studies. By contrast to discectomy, sequestrectomy was associated with significantly less operative time (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0121816