Phase transformations in a human tooth tissue at the initial stage of caries

The aim of the paper is to study phase transformations in solid tissues of the human teeth during the development of fissure caries by Raman and fluorescence microspectroscopy. The study of the areas with fissure caries confirmed the assumption of the formation of a weak interaction between phosphat...

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Bibliographic Details
Published in:PloS one 2015-04, Vol.10 (4), p.e0124008
Main Authors: Seredin, Pavel, Goloshchapov, Dmitry, Prutskij, Tatiana, Ippolitov, Yury
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anisotropy
Apatite
Bicuspid - chemistry
Bicuspid - pathology
Calcium phosphates
Calcium Phosphates - chemistry
Carbonates
Chemical reactions
Comparative analysis
Crystals
Demineralization
Demineralizing
Dental caries
Dental Caries - diagnosis
Dental Caries - pathology
Dental enamel
Dental Enamel - chemistry
Dental Enamel - pathology
Dentistry
Disease Progression
Durapatite - chemistry
Enamel
Female
Fluorescence
Humans
Hydroxyapatite
Hydroxyapatites
Male
Materials science
Metabolism
Microorganisms
Misalignment
Molar - chemistry
Molar - pathology
Molecular structure
Nondestructive testing
Organic acids
Phase transitions
Phosphate minerals
Physics
Solid state physics
Spectrometry, Fluorescence
Spectrum analysis
Spectrum Analysis, Raman
Systematic review
Teeth
Tissues
Tooth Extraction
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Summary:The aim of the paper is to study phase transformations in solid tissues of the human teeth during the development of fissure caries by Raman and fluorescence microspectroscopy. The study of the areas with fissure caries confirmed the assumption of the formation of a weak interaction between phosphate apatite enamel and organic acids (products of microorganisms). The experimental results obtained with by Raman microspectroscopy showed the formation of dicalcium phosphate dihydrate - CaHPO4-2H2O in the area of mural demineralization of carious fissure. A comparative analysis of structural and spectroscopic data for the intact and carious enamel shows that emergence of a more soluble phase - carbonate-substituted hydroxyapatite - is typical for the initial stage of caries. It is shown that microareas of dental hard tissues in the carious fissure due to an emerging misorientation of apatite crystals have a higher fluorescence yield than the area of the intact enamel. These areas can be easily detected even prior to a deep demineralization (white spot stage) for the case of irreversibly changed organomineral complex and intensive removal of the mineral component.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0124008