Comparison of operative and non-operative treatment of acute undisplaced or minimally-displaced scaphoid fractures: a meta-analysis of randomized controlled trials

• Published in: PloS one 2015-05, Vol.10 (5), p.e0125247-e0125247
• Main Authors: Shen, Longxiang, Tang, Jianfei, Luo, Congfeng, Xie, Xuetao, An, Zhiquan, Zhang, Changqing
• Format: Article
• Language: English
• Subjects: Adults; Bone surgery; Care and treatment; Casts; Clinical trials; Comparative analysis; Development and progression; Displacement; Fractures; Fractures, Bone - surgery; Fractures, Bone - therapy; Hand injuries; Hand Strength; Handbooks; Humans; Incidence; Medical ethics; Meta-analysis; Orthopedics; Patient outcomes; Patients; Postoperative Complications - epidemiology; Publication Bias; Randomization; Randomized Controlled Trials as Topic; Range of Motion, Articular; Recovery of Function; Scaphoid Bone - injuries; Studies; Surgery; Treatment Outcome; Weapons of mass destruction
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0125247

Traditionally, acute undisplaced or minimally-displaced scaphoid fractures are treated by casting in short- or long-arm casts. Although reports have shown that operative treatment is safe, effective and produces satisfactory results, outcomes from current studies comparing these two methods are questionable. The aim of this meta-analysis was to evaluate the effects of operative versus non-operative treatment for acute undisplaced or minimally-displaced scaphoid fractures in adults. Computerized searches were performed without language restrictions and all randomized controlled studies providing information on the effects of operative versus non-operative treatment on the outcomes of acute undisplaced or minimally-displaced scaphoid fractures were included. The weighted and standard mean difference (WMD and SMD) or the relative risk (RR) were calculated for continuous or dichotomous data respectively. A total of six studies reported in seven publications were included, representing data on 340 fractures. Meta-analysis indicated that operative treatment resulted in significantly better functional outcomes in the short term when compared with non-operative treatment. Consistently, patients who accepted surgery had a more rapid return to work. Further, surgery was advantageous in preventing delayed union of the fractures, a finding supported by the results of analysis of the time to fracture union. A number-needed-to-treat analysis revealed that more than 20 patients would have to undergo operative treatment to prevent one delayed union. Acute undisplaced or minimally-displaced scaphoid fractures demonstrate faster recovery with operative treatment; however, the current meta-analysis does not provide evidence supporting the routine use of operative treatment for all acute undisplaced or minimally-displaced scaphoid fractures.