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Initial data on the molecular epidemiology of cryptosporidiosis in Lebanon

Cryptosporidium spp. represent a major public health problem worldwide and infect the gastrointestinal tract of both immunocompetent and immunocompromised persons. The prevalence of these parasites varies by geographic region, and no data are currently available in Lebanon. To promote an understandi...

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Bibliographic Details
Published in:PloS one 2015-05, Vol.10 (5), p.e0125129-e0125129
Main Authors: Osman, Marwan, El Safadi, Dima, Benamrouz, Sadia, Guyot, Karine, Dei-Cas, Eduardo, Aliouat, El Moukhtar, Creusy, Colette, Mallat, Hassan, Hamze, Monzer, Dabboussi, Fouad, Viscogliosi, Eric, Certad, Gabriela
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Language:English
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Summary:Cryptosporidium spp. represent a major public health problem worldwide and infect the gastrointestinal tract of both immunocompetent and immunocompromised persons. The prevalence of these parasites varies by geographic region, and no data are currently available in Lebanon. To promote an understanding of the epidemiology of cryptosporidiosisin this country, the main aim of this study was to determine the prevalence Cryptosporidium in symptomatic hospitalized patients, and to analyze the genetic diversity of the corresponding isolates. Fecal specimens were collected in four hospitals in North Lebanon from 163 patients (77 males and 86 females, ranging in age from 1 to 88 years, with a mean age of 22 years) presenting gastrointestinal disorders during the period July to December 2013. The overall prevalence of Cryptosporidium spp. infection obtained by modified Ziehl-Neelsen staining and/or nested PCR was 11%, and children
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0125129