Dengue virus infections among Haitian and expatriate non-governmental organization workers--Léogane and Port-au-Prince, Haiti, 2012

In October 2012, the Haitian Ministry of Health and the US CDC were notified of 25 recent dengue cases, confirmed by rapid diagnostic tests (RDTs), among non-governmental organization (NGO) workers. We conducted a serosurvey among NGO workers in Léogane and Port-au-Prince to determine the extent of...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2014-10, Vol.8 (10), p.e3269-e3269
Main Authors: Salyer, Stephanie J, Ellis, Esther M, Salomon, Corvil, Bron, Christophe, Juin, Stanley, Hemme, Ryan R, Hunsperger, Elizabeth, Jentes, Emily S, Magloire, Roc, Tomashek, Kay M, Desormeaux, Anne Marie, Muñoz-Jordán, Jorge L, Etienne, Lesly, Beltran, Manuela, Sharp, Tyler M, Moffett, Daphne, Tappero, Jordan, Margolis, Harold S, Katz, Mark A
Format: Article
Language:English
Subjects:
Adult
Aedes
Aedes aegypti
Aged
Animals
Antibodies, Viral - blood
Biology and Life Sciences
Demographic aspects
Dengue
Dengue - epidemiology
Dengue - etiology
Dengue - transmission
Dengue fever
Dengue virus
Dengue Virus - immunology
Disease control
Distribution
Expatriates
Female
Haiti - epidemiology
Humans
Male
Medicine and Health Sciences
Middle Aged
Mosquitoes
NGOs
Nongovernmental organizations
People and places
Risk Factors
Time Factors
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Summary:In October 2012, the Haitian Ministry of Health and the US CDC were notified of 25 recent dengue cases, confirmed by rapid diagnostic tests (RDTs), among non-governmental organization (NGO) workers. We conducted a serosurvey among NGO workers in Léogane and Port-au-Prince to determine the extent of and risk factors for dengue virus infection. Of the total 776 staff from targeted NGOs in Léogane and Port-au-Prince, 173 (22%; 52 expatriates and 121 Haitians) participated. Anti-dengue virus (DENV) IgM antibody was detected in 8 (15%) expatriates and 9 (7%) Haitians, and DENV non-structural protein 1 in one expatriate. Anti-DENV IgG antibody was detected in 162 (94%) participants (79% of expatriates; 100% of Haitians), and confirmed by microneutralization testing as DENV-specific in 17/34 (50%) expatriates and 42/42 (100%) Haitians. Of 254 pupae collected from 68 containers, 65% were Aedes aegypti; 27% were Ae. albopictus. Few NGO workers reported undertaking mosquito-avoidance action. Our findings underscore the risk of dengue in expatriate workers in Haiti and Haitians themselves.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0003269