Characteristics of the Delayed or Refusal Therapy in Breast Cancer Patients: A Longitudinal Population-Based Study in Taiwan

The evidence indicated breast cancer was a cancer with high survival rate. However, there were still some breast cancer patients delaying or refusing therapy. So we conducted a cohort study to explore the relationship between characteristics of breast cancer patients and delay or refusal of therapy...

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Bibliographic Details
Published in:PloS one 2015-06, Vol.10 (6), p.e0131305-e0131305
Main Authors: Chen, Su Jing, Kung, Pei-Tseng, Huang, Kuang Hua, Wang, Yueh-Hsin, Tsai, Wen-Chen
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis
Breast cancer
Breast Neoplasms - diagnosis
Breast Neoplasms - mortality
Cancer
Cancer patients
Cancer research
Cancer therapies
Cancer treatment
Comorbidity
Delay
Diagnostic systems
Disease-Free Survival
Female
Hazards
Humans
Illnesses
Mathematical models
Medical diagnosis
Middle Aged
Mortality
Patients
Population studies
Population-based studies
Proportional Hazards Models
Registries
Regression analysis
Retrospective Studies
Statistical analysis
Statistical models
Statistical tests
Survival
Survival Rate
Taiwan - epidemiology
Therapy
Treatment Refusal
Urbanization
Womens health
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Summary:The evidence indicated breast cancer was a cancer with high survival rate. However, there were still some breast cancer patients delaying or refusing therapy. So we conducted a cohort study to explore the relationship between characteristics of breast cancer patients and delay or refusal of therapy within four months after cancer diagnosed. This was a retrospective national population-based study from 2004 to 2010 in Taiwan. This study included 35,095 patients with new diagnosis breast cancer from Taiwan Cancer Registry Database. Several analysis methods, including t test, Chi-square test, generalized estimating equations of logistic regression analysis, and Cox proportional hazards model, were performed to explore the characteristics of these patients and the relative risk of mortality with delay or refusal of therapy. Our study showed that the overall survival rates were significantly different (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0131305