Effect of Maximal Apnoea Easy-Going and Struggle Phases on Subarachnoid Width and Pial Artery Pulsation in Elite Breath-Hold Divers

• Published in: PloS one 2015-08, Vol.10 (8), p.e0135429-e0135429
• Main Authors: Winklewski, Pawel J, Barak, Otto, Madden, Dennis, Gruszecka, Agnieszka, Gruszecki, Marcin, Guminski, Wojciech, Kot, Jacek, Frydrychowski, Andrzej F, Drvis, Ivan, Dujic, Zeljko
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Analysis; Apnea; Backscattering; Blood; Blood flow; Blood Flow Velocity - physiology; Blood Pressure; Breath Holding; Breathing; Case-Control Studies; Cerebral Arteries - physiology; Cerebral blood flow; Cerebrovascular Circulation - physiology; Doppler effect; Echocardiography; EKG; Electrocardiography; Female; Flow velocity; Healthy Volunteers; Heart diseases; Heart Rate; Humans; Hypertension; I.R. radiation; Informatics; Infrared radiation; Intracranial pressure; Male; Medicine; Near infrared radiation; Oscillations; Oximetry; Physiology; Pial artery; Probes; Pulsation; Radiation; Respiration; Sleep; Sleep apnea; Sleep disorders; Subarachnoid space; Subarachnoid Space - physiology; Thorax; Ultrasonic scanners; Ultrasound; Veins & arteries; Velocity; Wavelet Analysis; Wavelet transforms
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0135429

The aim of the study was to assess changes in subarachnoid space width (sas-TQ), the marker of intracranial pressure (ICP), pial artery pulsation (cc-TQ) and cardiac contribution to blood pressure (BP), cerebral blood flow velocity (CBFV) and cc-TQ oscillations throughout the maximal breath hold in elite apnoea divers. Non-invasive assessment of sas-TQ and cc-TQ became possible due to recently developed method based on infrared radiation, called near-infrared transillumination/backscattering sounding (NIR-T/BSS). The experimental group consisted of seven breath-hold divers (six men). During testing, each participant performed a single maximal end-inspiratory breath hold. Apnoea consisted of the easy-going and struggle phases (characterised by involuntary breathing movements (IBMs)). Heart rate (HR) was determined using a standard ECG. BP was assessed using the photoplethysmography method. SaO2 was monitored continuously with pulse oximetry. A pneumatic chest belt was used to register thoracic and abdominal movements. Cerebral blood flow velocity (CBFV) was estimated by a 2-MHz transcranial Doppler ultrasonic probe. sas-TQ and cc-TQ were measured using NIR-T/BSS. Wavelet transform analysis was performed to assess cardiac contribution to BP, CBFV and cc-TQ oscillations. Mean BP and CBFV increased compared to baseline at the end of the easy phase and were further augmented by IBMs. cc-TQ increased compared to baseline at the end of the easy phase and remained stable during the IBMs. HR did not change significantly throughout the apnoea, although a trend toward a decrease during the easy phase and recovery during the IBMs was visible. Amplitudes of BP, CBFV and cc-TQ were augmented. sas-TQ and SaO2 decreased at the easy phase of apnoea and further decreased during the IBMs. Apnoea increases intracranial pressure and pial artery pulsation. Pial artery pulsation seems to be stabilised by the IBMs. Cardiac contribution to BP, CBFV and cc-TQ oscillations does not change throughout the apnoea.