Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study

The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumo...

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Bibliographic Details
Published in:PloS one 2015-09, Vol.10 (9), p.e0137546-e0137546
Main Authors: Sugino, Hirotoshi, Tsumura, Shigeru, Kunimoto, Masaru, Noda, Masuhiro, Chikuie, Daisuke, Noda, Chieko, Yamashita, Mariko, Watanabe, Hiroshi, Ishii, Hidemasa, Tashiro, Toru, Iwata, Kazuhiro, Kono, Takashi, Tsumura, Kaoru, Sumiya, Takahiro, Takeno, Sachio, Hirakawa, Katsuhiro
Format: Article
Language:English
Subjects:
Child, Preschool
Children
Complications and side effects
Ear, Middle - immunology
Ear, Middle - physiopathology
Female
Funding
Haemophilus influenzae
Humans
Immunization
Infant
Infants
Inflammation
Inflammation - immunology
Inflammation - pathology
Inflammation - prevention & control
Inoculation
Japan
Media
Middle ear
Middle Ear Ventilation
Otitis media
Otitis Media - immunology
Otitis Media - physiopathology
Otitis Media - prevention & control
Otolaryngology
Physicians
Physiological aspects
Pneumococcal vaccines
Pneumococcal Vaccines - administration & dosage
Practice Guidelines as Topic
Prevention
Quality
Retrospective Studies
Streptococcus pneumoniae
Studies
Vaccines
Vaccines, Conjugate - administration & dosage
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Summary:The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumococcal conjugate vaccine was released in Japan in February 2010. In Hiroshima City, public funding allowing free inoculation with this vaccine was initiated from January 2011, and the number of vaccinated individuals has since increased dramatically. This study investigated changes in the number of myringotomies performed to treat acute otitis media during the 5-year period from January 2008 to December 2012 at two hospitals and five clinics in the Asa Area of Hiroshima City, Japan. A total of 3,165 myringotomies for acute otitis media were performed. The rate of procedures per child-year performed in
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0137546