Initial Experience with a Wireless Ultrasound-Guided Vacuum-Assisted Breast Biopsy Device

• Published in: PloS one 2015-12, Vol.10 (12), p.e0144046-e0144046
• Main Authors: Choi, E-Ryung, Han, Boo-Kyung, Ko, Eun Sook, Ko, Eun Young, Choi, Ji Soo, Cho, Eun Yoon, Nam, Seok Jin
• Format: Article
• Language: English
• Subjects: Adult; Aged; Automation; Biopsy; Biopsy, Needle - instrumentation; Biopsy, Needle - methods; Bleeding; Breast; Breast - pathology; Breast biopsy; Breast cancer; Breast Neoplasms - pathology; Breasts; Calcification; Calcinosis - pathology; Cancer; Carcinoma, Ductal, Breast - pathology; Carcinoma, Intraductal, Noninfiltrating - pathology; Care and treatment; Complications; Cores; Diagnostic systems; False Negative Reactions; Female; Health aspects; Humans; Image-Guided Biopsy - instrumentation; Image-Guided Biopsy - methods; Lesions; Malignancy; Mammography; Medical diagnosis; Medical equipment; Medical materials; Medicine; Middle Aged; Pathology; Patient outcomes; Science; Surgery; Ultrasonography - instrumentation; Ultrasonography - methods; Ultrasound; Vacuum; Wireless Technology - instrumentation
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0144046

To determine the imaging characteristic of frequent target lesions of wireless ultrasound (US)-guided, vacuum-assisted breast biopsy (Wi-UVAB) and to evaluate diagnostic yield, accuracy and complication of the device in indeterminate breast lesions. From March 2013 to October 2014, 114 women (age range, 29-76 years; mean age, 50.0 years) underwent Wi-UVAB using a 13-gauge needle (Mammotome Elite®; Devicor Medical Products, Cincinnati, OH, USA). In 103 lesions of 96 women with surgical (n = 81) or follow-up (n = 22) data, complications, biopsy procedure, imaging findings of biopsy targets and histologic results were reviewed. Mean number of biopsy cores was 10 (range 4-25). Nine patients developed moderate bleeding. All lesions were suspicious on US, and included non-mass lesions (67.0%) and mass lesions (33.0%). Visible calcifications on US were evident in 57.3% of the target lesions. Most of the lesions (93.2%) were nonpalpable. Sixty-six (64.1%) were malignant [ductal carcinoma in situ (DCIS) rate, 61%] and 12 were high-risk lesions (11.7%). Histologic underestimation was identified in 11 of 40 (27.5%). DCIS cases and in 3 of 9 (33.3%) high-risk lesions necessitating surgery. There was no false-negative case. Wi-UVAB is very handy and advantageous for US-unapparent non-mass lesions to diagnose DCIS, especially for calcification cases. Histologic underestimation is unavoidable; still, Wi-UVAB is safe and accurate to diagnose a malignancy.