Comparing the Ability of Anthropometric Indicators in Identifying Metabolic Syndrome in HIV Patients

• Published in: PloS one 2016-02, Vol.11 (2), p.e0149905-e0149905
• Main Authors: Beraldo, Rebeca Antunes, Meliscki, Gabriela Cristina, Silva, Bruna Ramos, Navarro, Anderson Marliere, Bollela, Valdes Roberto, Schmidt, André, Foss-Freitas, Maria Cristina
• Format: Article
• Language: English
• Subjects: Adipose tissue; Adult; Anthropometry; Antiretroviral agents; Antiretroviral drugs; Biochemical tests; Biology and Life Sciences; Blood pressure; Body mass; Body mass index; Body measurements; Cardiovascular disease; Cardiovascular diseases; Cholesterol; Classification; Complications; Demographic aspects; Diseases and pests; Drug therapy; Fasting; Female; Females; Health risk assessment; Health risks; Heart diseases; High density lipoprotein; Highly active antiretroviral therapy; Hip; HIV; HIV Infections - complications; HIV patients; Human immunodeficiency virus; Humans; Indicators; Laboratory testing; Low density lipoprotein; Male; Males; Medicine and Health Sciences; Metabolic syndrome; Metabolic Syndrome - complications; Metabolic Syndrome - diagnosis; Metabolic syndrome X; Obesity; Patients; Predictive Value of Tests; Risk factors; ROC Curve; Side effects; Social Sciences; Thigh; Triglycerides
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0149905

Highly active antiretroviral therapy (HAART) can cause side effects in HIV patients, as the metabolic syndrome. Early identification of risk for development of cardiovascular diseases using available reliable and practical methods is fundamental. On this basis, the aim of this study was to compare the effectiveness of anthropometric indicators to identify metabolic syndrome in HIV patients on HAART. It is a cross-sectional study. A number of 280 stable HIV patients were studied. It measured weight, height, waist circumference (WC), hip circumference (HP), thigh circumference (TC) and calculated body mass index (BMI), body adiposity index (BAI), waist to hip ratio (WHR) and waist to thigh ratio (WTR). There was also a performance of biochemical tests of lipid profile and fasting glucose. Systemic blood pressure was measured. The criteria proposed by the National Cholesterol Education Program III (NCEP-ATP III) to metabolic syndrome classification was used. Individuals were divided in groups with or without metabolic alterations and their anthropometric indicators were compared. Receiver operating characteristic (ROC) curves were designed for each anthropometric indicator using the metabolic syndrome classification to identify sensitivity and specificity. WC was a good tool to identify each metabolic disorder separately: total cholesterol (only females, p