A Human "eFP" Browser for Generating Gene Expression Anatograms

Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same exp...

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Bibliographic Details
Published in:PloS one 2016-03, Vol.11 (3), p.e0150982-e0150982
Main Authors: Patel, Rohan V, Hamanishi, Erin T, Provart, Nicholas J
Format: Article
Language:English
Subjects:
Acids
Biology and Life Sciences
Computer and Information Sciences
Databases, Genetic
Datasets
Fluorescence
Gene expression
Gene Expression Profiling - methods
Genome-wide association studies
Genomes
Genomics
Humans
Innovations
Internet resources
Medicine and Health Sciences
Mesothelioma
Proteins
Representations
Research and Analysis Methods
Software
Transcriptome
Visualization
Web Browser
Web browsers
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Description
Summary:Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0150982