Loading…
A Human "eFP" Browser for Generating Gene Expression Anatograms
Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same exp...
Saved in:
Published in: | PloS one 2016-03, Vol.11 (3), p.e0150982-e0150982 |
---|---|
Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333 |
---|---|
cites | cdi_FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333 |
container_end_page | e0150982 |
container_issue | 3 |
container_start_page | e0150982 |
container_title | PloS one |
container_volume | 11 |
creator | Patel, Rohan V Hamanishi, Erin T Provart, Nicholas J |
description | Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources. |
doi_str_mv | 10.1371/journal.pone.0150982 |
format | article |
fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1771446032</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A453531442</galeid><doaj_id>oai_doaj_org_article_872a630a49bb47dc961e3103a5c9480b</doaj_id><sourcerecordid>A453531442</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333</originalsourceid><addsrcrecordid>eNqNkltv0zAUxyMEYhf4BgiiTULw0OJ7nBdQmXapNGmI26t16jhpqsTu7ATGt8dts6lBe0B-sHX8O__jc_xPklcYTTHN8IeV672FZrp21kwR5iiX5ElyiHNKJoIg-nTvfJAchbBCiFMpxPPkgIicM47YYfJpll71Ldj0xFx8OUk_e_c7GJ-WzqeXxhoPXW2r7TE9v1t7E0LtbDqz0LnKQxteJM9KaIJ5OezHyY-L8-9nV5Prm8v52ex6okVOugmTlGFquOC8QBnhBSt0pmEh8jLXOQDmwEQOppCSlDIrjcSsQIiUJWeSUUqPkzc73XXjghp6DwpnGWZMIEoiMd8RhYOVWvu6Bf9HOajVNuB8pcB3tW6MkhkBQRGwfLFgWaFzgQ3FiALXOZNoEbU-DtX6RWsKbWznoRmJjm9svVSV-6VYJikiLAq8GwS8u-1N6FRbB22aBqxx_fbdBDMh5Kaz03_Qx7sbqApiA7UtXayrN6JqxjjlNIIbavoIFVdh2lpHo5R1jI8S3o8SItOZu66CPgQ1__b1_9mbn2P27R67NNB0y-CavovuCWOQ7UDtXQjelA9DxkhtfH4_DbXxuRp8HtNe73_QQ9K9selfsDH0Xw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1771446032</pqid></control><display><type>article</type><title>A Human "eFP" Browser for Generating Gene Expression Anatograms</title><source>PubMed (Medline)</source><source>Publicly Available Content (ProQuest)</source><creator>Patel, Rohan V ; Hamanishi, Erin T ; Provart, Nicholas J</creator><contributor>Esteban, Francisco J.</contributor><creatorcontrib>Patel, Rohan V ; Hamanishi, Erin T ; Provart, Nicholas J ; Esteban, Francisco J.</creatorcontrib><description>Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0150982</identifier><identifier>PMID: 26954504</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acids ; Biology and Life Sciences ; Computer and Information Sciences ; Databases, Genetic ; Datasets ; Fluorescence ; Gene expression ; Gene Expression Profiling - methods ; Genome-wide association studies ; Genomes ; Genomics ; Humans ; Innovations ; Internet resources ; Medicine and Health Sciences ; Mesothelioma ; Proteins ; Representations ; Research and Analysis Methods ; Software ; Transcriptome ; Visualization ; Web Browser ; Web browsers</subject><ispartof>PloS one, 2016-03, Vol.11 (3), p.e0150982-e0150982</ispartof><rights>COPYRIGHT 2016 Public Library of Science</rights><rights>2016 Patel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2016 Patel et al 2016 Patel et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333</citedby><cites>FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1771446032/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1771446032?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26954504$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Esteban, Francisco J.</contributor><creatorcontrib>Patel, Rohan V</creatorcontrib><creatorcontrib>Hamanishi, Erin T</creatorcontrib><creatorcontrib>Provart, Nicholas J</creatorcontrib><title>A Human "eFP" Browser for Generating Gene Expression Anatograms</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.</description><subject>Acids</subject><subject>Biology and Life Sciences</subject><subject>Computer and Information Sciences</subject><subject>Databases, Genetic</subject><subject>Datasets</subject><subject>Fluorescence</subject><subject>Gene expression</subject><subject>Gene Expression Profiling - methods</subject><subject>Genome-wide association studies</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Humans</subject><subject>Innovations</subject><subject>Internet resources</subject><subject>Medicine and Health Sciences</subject><subject>Mesothelioma</subject><subject>Proteins</subject><subject>Representations</subject><subject>Research and Analysis Methods</subject><subject>Software</subject><subject>Transcriptome</subject><subject>Visualization</subject><subject>Web Browser</subject><subject>Web browsers</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNkltv0zAUxyMEYhf4BgiiTULw0OJ7nBdQmXapNGmI26t16jhpqsTu7ATGt8dts6lBe0B-sHX8O__jc_xPklcYTTHN8IeV672FZrp21kwR5iiX5ElyiHNKJoIg-nTvfJAchbBCiFMpxPPkgIicM47YYfJpll71Ldj0xFx8OUk_e_c7GJ-WzqeXxhoPXW2r7TE9v1t7E0LtbDqz0LnKQxteJM9KaIJ5OezHyY-L8-9nV5Prm8v52ex6okVOugmTlGFquOC8QBnhBSt0pmEh8jLXOQDmwEQOppCSlDIrjcSsQIiUJWeSUUqPkzc73XXjghp6DwpnGWZMIEoiMd8RhYOVWvu6Bf9HOajVNuB8pcB3tW6MkhkBQRGwfLFgWaFzgQ3FiALXOZNoEbU-DtX6RWsKbWznoRmJjm9svVSV-6VYJikiLAq8GwS8u-1N6FRbB22aBqxx_fbdBDMh5Kaz03_Qx7sbqApiA7UtXayrN6JqxjjlNIIbavoIFVdh2lpHo5R1jI8S3o8SItOZu66CPgQ1__b1_9mbn2P27R67NNB0y-CavovuCWOQ7UDtXQjelA9DxkhtfH4_DbXxuRp8HtNe73_QQ9K9selfsDH0Xw</recordid><startdate>20160308</startdate><enddate>20160308</enddate><creator>Patel, Rohan V</creator><creator>Hamanishi, Erin T</creator><creator>Provart, Nicholas J</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20160308</creationdate><title>A Human "eFP" Browser for Generating Gene Expression Anatograms</title><author>Patel, Rohan V ; Hamanishi, Erin T ; Provart, Nicholas J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acids</topic><topic>Biology and Life Sciences</topic><topic>Computer and Information Sciences</topic><topic>Databases, Genetic</topic><topic>Datasets</topic><topic>Fluorescence</topic><topic>Gene expression</topic><topic>Gene Expression Profiling - methods</topic><topic>Genome-wide association studies</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Humans</topic><topic>Innovations</topic><topic>Internet resources</topic><topic>Medicine and Health Sciences</topic><topic>Mesothelioma</topic><topic>Proteins</topic><topic>Representations</topic><topic>Research and Analysis Methods</topic><topic>Software</topic><topic>Transcriptome</topic><topic>Visualization</topic><topic>Web Browser</topic><topic>Web browsers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patel, Rohan V</creatorcontrib><creatorcontrib>Hamanishi, Erin T</creatorcontrib><creatorcontrib>Provart, Nicholas J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Nursing and Allied Health Source</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patel, Rohan V</au><au>Hamanishi, Erin T</au><au>Provart, Nicholas J</au><au>Esteban, Francisco J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Human "eFP" Browser for Generating Gene Expression Anatograms</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2016-03-08</date><risdate>2016</risdate><volume>11</volume><issue>3</issue><spage>e0150982</spage><epage>e0150982</epage><pages>e0150982-e0150982</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>26954504</pmid><doi>10.1371/journal.pone.0150982</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1932-6203 |
ispartof | PloS one, 2016-03, Vol.11 (3), p.e0150982-e0150982 |
issn | 1932-6203 1932-6203 |
language | eng |
recordid | cdi_plos_journals_1771446032 |
source | PubMed (Medline); Publicly Available Content (ProQuest) |
subjects | Acids Biology and Life Sciences Computer and Information Sciences Databases, Genetic Datasets Fluorescence Gene expression Gene Expression Profiling - methods Genome-wide association studies Genomes Genomics Humans Innovations Internet resources Medicine and Health Sciences Mesothelioma Proteins Representations Research and Analysis Methods Software Transcriptome Visualization Web Browser Web browsers |
title | A Human "eFP" Browser for Generating Gene Expression Anatograms |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T22%3A39%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Human%20%22eFP%22%20Browser%20for%20Generating%20Gene%20Expression%20Anatograms&rft.jtitle=PloS%20one&rft.au=Patel,%20Rohan%20V&rft.date=2016-03-08&rft.volume=11&rft.issue=3&rft.spage=e0150982&rft.epage=e0150982&rft.pages=e0150982-e0150982&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0150982&rft_dat=%3Cgale_plos_%3EA453531442%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c692t-483413e5655d0725d4dc7cab69f9c9aa15a469aed882f87fe814d002ff5484333%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1771446032&rft_id=info:pmid/26954504&rft_galeid=A453531442&rfr_iscdi=true |