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Benefits of Bifidobacterium breve M-16V Supplementation in Preterm Neonates - A Retrospective Cohort Study

Systematic reviews of randomised controlled trials report that probiotics reduce the risk of necrotising enterocolitis (NEC) in preterm neonates. To determine whether routine probiotic supplementation (RPS) to preterm neonates would reduce the incidence of NEC. The incidence of NEC ≥ Stage II and al...

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Bibliographic Details
Published in:PloS one 2016-03, Vol.11 (3), p.e0150775-e0150775
Main Authors: Patole, Sanjay K, Rao, Shripada C, Keil, Anthony D, Nathan, Elizabeth A, Doherty, Dorota A, Simmer, Karen N
Format: Article
Language:English
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Summary:Systematic reviews of randomised controlled trials report that probiotics reduce the risk of necrotising enterocolitis (NEC) in preterm neonates. To determine whether routine probiotic supplementation (RPS) to preterm neonates would reduce the incidence of NEC. The incidence of NEC ≥ Stage II and all-cause mortality was compared for an equal period of 24 months 'before' (Epoch 1) and 'after' (Epoch 2) RPS with Bifidobacterium breve M-16V in neonates
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0150775