Documenting Penicillin Allergy: The Impact of Inconsistency

Allergy documentation is frequently inconsistent and incomplete. The impact of this variability on subsequent treatment is not well described. To determine how allergy documentation affects subsequent antibiotic choice. Retrospective, cohort study. 232,616 adult patients seen by 199 primary care pro...

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Bibliographic Details
Published in:PloS one 2016-03, Vol.11 (3), p.e0150514-e0150514
Main Authors: Shah, Nirav S, Ridgway, Jessica P, Pettit, Natasha, Fahrenbach, John, Robicsek, Ari
Format: Article
Language:English
Subjects:
Allergens
Allergies
Ambulatory care
Amides
Amoxicillin
Antibiotics
Antimicrobial agents
Beta lactam antibiotics
Binomial distribution
Biology and Life Sciences
Cephalosporins
Clindamycin
Complications and side effects
Confidence intervals
Documentation
Drug Hypersensitivity - diagnosis
Female
Fluoroquinolones
Health care
Hospitals
Humans
Hypersensitivity
Internal medicine
Male
Medical records
Medicine
Medicine and Health Sciences
Middle Aged
Patients
Penicillin
Penicillins - adverse effects
People and Places
Physicians
Primary care
Retrospective Studies
Sensitivity and Specificity
Staphylococcus infections
Supply and demand
Vancomycin
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Summary:Allergy documentation is frequently inconsistent and incomplete. The impact of this variability on subsequent treatment is not well described. To determine how allergy documentation affects subsequent antibiotic choice. Retrospective, cohort study. 232,616 adult patients seen by 199 primary care providers (PCPs) between January 1, 2009 and January 1, 2014 at an academic medical system. Inter-physician variation in beta-lactam allergy documentation; antibiotic treatment following beta-lactam allergy documentation. 15.6% of patients had a reported beta-lactam allergy. Of those patients, 39.8% had a specific allergen identified and 22.7% had allergic reaction characteristics documented. Variation between PCPs was greater than would be expected by chance (all p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0150514