Intranasal Volume Changes Caused by the Endoscopic Endonasal Transsphenoidal Approach and Their Effects on Nasal Functions

We evaluated postoperative changes in nasal cavity volume and their effects on nasal function and symptoms after endoscopic endonasal transsphenoidal approach for antero-central skull base surgery. Retrospective chart review at a tertiary referral center. We studied 92 patients who underwent binostr...

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Bibliographic Details
Published in:PloS one 2016-03, Vol.11 (3), p.e0151531-e0151531
Main Authors: Kim, Do Hyun, Hong, Yong-Kil, Jeun, Sin-Soo, Park, Yong Jin, Kim, Soo Whan, Cho, Jin Hee, Kim, Boo Young, Han, Sungwoo, Lee, Yong Joo, Hwang, Jae Hyung, Kim, Sung Won
Format: Article
Language:English
Subjects:
Adult
Aged
Biology and Life Sciences
Chemoreception
Computed tomography
Endoscopy
Endoscopy - adverse effects
Endoscopy - instrumentation
Endoscopy - methods
Female
Health aspects
Hospitals
Humans
Male
Medical personnel
Medicine
Medicine and Health Sciences
Middle Aged
Nasal Cavity - pathology
Nasal Cavity - physiology
Nasal Cavity - surgery
Nasal fossa
Neurosurgery
Nose
Olfaction
Otolaryngology
Patients
People and Places
Physiological aspects
Research and Analysis Methods
Retrospective Studies
Sinuses
Skull
Skull Base Neoplasms - surgery
Smell
Surgery
Surgical outcomes
Tumor removal
Tumors
Young Adult
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Summary:We evaluated postoperative changes in nasal cavity volume and their effects on nasal function and symptoms after endoscopic endonasal transsphenoidal approach for antero-central skull base surgery. Retrospective chart review at a tertiary referral center. We studied 92 patients who underwent binostril, four-hand, endoscopic endonasal transsphenoidal approach surgery using the bilateral modified nasoseptal rescue flap technique. Pre- and postoperative paranasal computed tomography and the Mimics® program were used to assess nasal cavity volume changes at three sections. We also performed several pre- and postoperative tests, including the Connecticut Chemosensory Clinical Research Center test, Cross-Cultural Smell Identification Test, Nasal Obstruction Symptoms Evaluation, and Sino-Nasal Outcome Test-20. In addition, a visual analog scale was used to record subjective symptoms. We compared these data with the pre- and postoperative nasal cavity volumes. Three-dimensional, objective increases in nasal passage volumes were evident between the inferior and middle turbinates (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0151531