Effect of Electrode Belt and Body Positions on Regional Pulmonary Ventilation- and Perfusion-Related Impedance Changes Measured by Electric Impedance Tomography

• Published in: PloS one 2016-06, Vol.11 (6), p.e0155913-e0155913
• Main Authors: Ericsson, Elin, Tesselaar, Erik, Sjöberg, Folke
• Format: Article
• Language: English
• Subjects: Biology and Life Sciences; Breathing; Care and treatment; Change detection; Computer and Information Sciences; Electric Impedance; Electrical impedance; Electrodes; Engineering and Technology; Gravity; Health sciences; Healthy Volunteers; Humans; Impedance; Lung - diagnostic imaging; Lung - physiopathology; Lung diseases; Lungs; Male; Mechanical ventilation; Medical imaging; Medicine and Health Sciences; Methods; Morphology; Perfusion; Perfusion - adverse effects; Physical Sciences; Posture; Posture - physiology; Pulmonary Ventilation - physiology; Research and Analysis Methods; Respiratory distress syndrome; Studies; Thorax; Tomography; Ventilation; Ventilator-Induced Lung Injury - diagnosis; Ventilator-Induced Lung Injury - diagnostic imaging; Ventilator-Induced Lung Injury - physiopathology; Ventilators
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0155913

Ventilator-induced or ventilator-associated lung injury (VILI/VALI) is common and there is an increasing demand for a tool that can optimize ventilator settings. Electrical impedance tomography (EIT) can detect changes in impedance caused by pulmonary ventilation and perfusion, but the effect of changes in the position of the body and in the placing of the electrode belt on the impedance signal have not to our knowledge been thoroughly evaluated. We therefore studied ventilation-related and perfusion-related changes in impedance during spontaneous breathing in 10 healthy subjects in five different body positions and with the electrode belt placed at three different thoracic positions using a 32-electrode EIT system. We found differences between regions of interest that could be attributed to changes in the position of the body, and differences in impedance amplitudes when the position of the electrode belt was changed. Ventilation-related changes in impedance could therefore be related to changes in the position of both the body and the electrode belt. Perfusion-related changes in impedance were probably related to the interference of major vessels. While these findings give us some insight into the sources of variation in impedance signals as a result of changes in the positions of both the body and the electrode belt, further studies on the origin of the perfusion-related impedance signal are needed to improve EIT further as a tool for the monitoring of pulmonary ventilation and perfusion.