Dermoscopy of Melanomas on the Trunk and Extremities in Asians

• Published in: PloS one 2016-07, Vol.11 (7), p.e0158374-e0158374
• Main Authors: Mun, Je-Ho, Ohn, Jungyoon, Kim, Woo-Il, Park, Sung-Min, Kim, Moon-Bum
• Format: Article
• Language: English
• Subjects: Algorithms; Asian Continental Ancestry Group; Asymmetry; Biology and Life Sciences; Cancer diagnosis; Care and treatment; Comparative analysis; Dermatology; Dermoscopy; Diagnosis; Diagnostic software; Diagnostic systems; Extremities; Extremities - diagnostic imaging; Extremities - pathology; Female; Globules; Hospitals; Humans; Lesions; Male; Medical diagnosis; Medicine; Medicine and Health Sciences; Melanoma; Melanoma - chemistry; Melanoma - diagnostic imaging; Melanoma - pathology; Microscopy; Patients; Pediatrics; Physical Sciences; Population; Population studies; Populations; Regression analysis; Republic of Korea; Skin; Skin cancer; Skin Neoplasms - blood supply; Skin Neoplasms - diagnostic imaging; Skin Neoplasms - pathology; Statistical analysis; Studies; Symmetry; Torso - diagnostic imaging; Torso - pathology; Ulcers
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0158374

The incidence of melanoma among the Asian population is lower compared to that among the Western European population. These populations differed in their most common histopathologic subtypes, acral lentiginous melanoma being the most common in the Asian population. Although the dermoscopic features of the melanomas on the acral skin have been thoroughly investigated in the Asian population, studies concerning the dermoscopic patterns of melanomas on the non-acral skin have been scarce. The aim of this study was to investigate the dermoscopic patterns of melanomas on the trunk and extremities in the Asian population. To achieve this, we evaluated the dermoscopic patterns of 22 primary melanomas diagnosed at two university hospitals in Korea. In addition, 100 benign melanocytic lesions were included as the control group for comparative analysis. A P value less than 0.05 was regarded as statistically significant. Melanoma-associated dermoscopic features such as asymmetry (odds ratio [OR], 30.00), multicolor pattern (OR, 30.12), blotches (OR, 13.50), blue white veils (OR, 15.75), atypical pigment networks (OR, 9.71), irregular peripheral streaks (OR, 6.30), atypical vascular patterns (OR, 11.50), ulcers (OR, 15.83), atypical dots/globules (OR, 3.15), shiny white lines (OR, 5.88), and regression structures (OR, 7.06) were more commonly observed in patients with melanomas than in patients of the control group. The mean dermoscopic scores obtained on the 7-point checklist, revised 7-point checklist, 3-point checklist, ABCD rule, and CASH algorithm were 5.36, 3.41, 2.05, 6.89, and 9.68, respectively, in the primary melanomas, and 1.33, 0.93, 0.46, 2.45, and 3.60, respectively, in the control group (all, P < 0.001). The present study showed that melanoma-related dermoscopic patterns were common in Asian patients. Dermoscopy is a reliable diagnostic tool for the melanomas of the trunk and extremities in the Asian populations.