Community Willingness to Participate in a Dengue Study in Aceh Province, Indonesia

• Published in: PloS one 2016-07, Vol.11 (7), p.e0159139
• Main Authors: Harapan, Harapan, Anwar, Samsul, Bustaman, Aslam, Radiansyah, Arsil, Angraini, Pradiba, Fasli, Riny, Salwiyadi, Salwiyadi, Bastian, Reza Akbar, Oktiviyari, Ade, Akmal, Imaduddin, Iqbalamin, Muhammad, Adil, Jamalul, Henrizal, Fenni, Darmayanti, Darmayanti, Pratama, Rovy, Fajar, Jonny Karunia, Setiawan, Abdul Malik, Imrie, Allison, Kuch, Ulrich, Groneberg, David Alexander, Sasmono, R Tedjo, Dhimal, Meghnath, Müller, Ruth
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; African Americans; Aged; Altruism; Analysis; Asian Americans; Biology and Life Sciences; Blood & organ donations; Cancer; Citizen participation; Clinical trials; Community involvement; Community participation; Community Participation - psychology; Correlation analysis; Demography; Dengue; Dengue - epidemiology; Dengue fever; Dengue virus; Dependent variables; Development and progression; Disease transmission; Distribution; Education; Environmental health; Epidemiology; Female; Fever; Genetic research; Health aspects; Heart attacks; Humans; Independent variables; Indonesia - epidemiology; Infections; Laboratories; Male; Medical research; Medical screening; Medicine; Medicine and Health Sciences; Middle Aged; Municipalities; People and Places; Physical Sciences; Prevalence; Regression analysis; Research and Analysis Methods; Socioeconomics; Studies; Surveillance; Surveys and Questionnaires; Systematic review; Tropical diseases; Vector-borne diseases; Viral diseases; Viruses; Young Adult
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0159139

Dengue virus infection is the most rapidly spreading vector-borne disease in the world. Essential research on dengue virus transmission and its prevention requires community participation. Therefore, it is crucial to understand the factors that are associated with the willingness of communities in high prevalence areas to participate in dengue research. The aim of this study was to explore factors associated with the willingness of healthy community members in Aceh province, Indonesia, to participate in dengue research that would require phlebotomy. A community-based cross-sectional study was carried out in nine regencies and municipalities of Aceh from November 2014 to March 2015. Interviews using a set of validated questionnaires were conducted to collect data on demography, history of dengue infection, socioeconomic status, and knowledge, attitude and practice regarding dengue fever. Two-step logistic regression and Spearman's rank correlation (rs) analysis were used to assess the influence of independent variables on dependent variables. Among 535 participants, less than 20% had a good willingness to participate in the dengue study. The factors associated with good willingness to participate were being female, working as a civil servant, private employee or entrepreneur, having a high socioeconomic status and good knowledge, attitude and practice regarding dengue. Good knowledge and attitude regarding dengue were positive independent predictors of willingness to participate (OR: 2.30 [95% CI: 1.36-3.90] and 3.73 [95% CI: 2.24-6.21], respectively). The willingness to participate in dengue research is very low among community members in Aceh, and the two most important associated factors are knowledge and attitude regarding dengue. To increase participation rate, efforts to improve the knowledge and attitude of community members regarding dengue fever and dengue-related research is required before such studies are launched.