Effects of Multidrug Resistant Tuberculosis Treatment on Patients' Health Related Quality of Life: Results from a Follow Up Study

At present, within the management of multidrug resistant tuberculosis (MDR-TB) much attention is being paid to the traditional microbiological and clinical indicators. Evaluation of the impact of MDR-TB treatment on patients' Health Related Quality of Life (HRQoL) has remained a neglected area....

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Bibliographic Details
Published in:PloS one 2016-07, Vol.11 (7), p.e0159560-e0159560
Main Authors: Ahmad, Nafees, Javaid, Arshad, Syed Sulaiman, Syed Azhar, Basit, Anila, Afridi, Afsar Khan, Jaber, Ammar Ali Saleh, Khan, Amer Hayat
Format: Article
Language:English
Subjects:
Adult
Analysis
Antitubercular Agents - therapeutic use
Balances (scales)
Care and treatment
Chemotherapy
Chronic illnesses
Clinical outcomes
Data collection
Diagnosis
Discipline
Disease
Drug resistance
Female
Follow-Up Studies
Gender
Hospitals
Humans
Male
Medical diagnosis
Medicine and Health Sciences
Mental depression
Mental health
Mortality
Multidrug resistance
Multidrug resistant organisms
Mycobacterium
Patients
Pharmaceutical sciences
Pharmacy
Prospective Studies
Psychiatry
Quality of Life
Studies
Surveys and Questionnaires
Tuberculosis
Tuberculosis, Multidrug-Resistant - drug therapy
Tuberculosis, Multidrug-Resistant - physiopathology
Variance analysis
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Summary:At present, within the management of multidrug resistant tuberculosis (MDR-TB) much attention is being paid to the traditional microbiological and clinical indicators. Evaluation of the impact of MDR-TB treatment on patients' Health Related Quality of Life (HRQoL) has remained a neglected area. To evaluate the impact of MDR-TB treatment on patients HRQoL, and determine the predictors of variability in HRQoL along the course of treatment. A prospective follow up study was conducted at the programmatic management unit for drug resistant TB of Lady Reading Hospital Peshawar. Culture confirmed eligible MDR-TB patients were asked to self complete SF-36v2 at the baseline visit, and subsequently after the completion of 12 months of treatment and at the end of treatment. A score of
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0159560