Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU

• Published in: PloS one 2016-11, Vol.11 (11), p.e0148736-e0148736
• Main Authors: Debus, Florian, Lefering, Rolf, Lechler, Philipp, Schwarting, Tim, Bockmann, Benjamin, Strasser, Erwin, Mand, Carsten, Ruchholtz, Steffen, Frink, Michael
• Format: Article
• Language: English
• Subjects: Adult; Biology and Life Sciences; Blood; Blood Banks; Blood cells; Blood Transfusion; Blood transfusions; Care and treatment; Critical care; Data processing; Documentation; Emergency medical care; Emergency medical services; Erythrocytes; Fatalities; Female; Hemorrhage; Hospitals; Humans; Injuries; Injury analysis; Injury Severity Score; Intensive care; Laboratories; Male; Medical care quality; Medical prognosis; Medicine; Medicine and Health Sciences; Middle Aged; Mortality; Patient Admission; Patient outcomes; Patients; People and Places; Quality standards; Retrospective Studies; Shock; Shock, Hemorrhagic - therapy; Studies; Therapy; Transfusion; Trauma; Trauma centers; Treatment Outcome
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0148736

Hemorrhagic shock remains one of the most common causes of death in severely injured patients. It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients. We retrospectively analyzed prospectively recorded data from the TraumaRegister DGU® and the TraumaNetzwerk DGU®. Inclusion criteria were Injury Severity Score (ISS) ≥ 16, primarily treated patients, and hospital admission 2 years before or after the audit process. Complete data sets of 18,573 patients were analyzed. Of 457 hospitals included, 33.3% had an in-house blood bank. In trauma centers with a blood bank (HospBB), packed red blood cells (PRBCs) (21.0% vs. 17.4%, p < 0.001) and fresh frozen plasma (FFP) (13.9% vs. 10.2%, p