Prevalence and Mortality-Related Factors of Multiple Myeloma in Taiwan

• Published in: PloS one 2016-12, Vol.11 (12), p.e0167227-e0167227
• Main Authors: Chen, Jia-Hong, Chung, Chi-Hsiang, Wang, Yung-Chih, Hsu, Shun-Neng, Huang, Wen-Yen, Chien, Wu-Chien
• Format: Article
• Language: English
• Subjects: Age; Aged; Aged, 80 and over; Analysis; Biology and Life Sciences; Death; Diagnosis; Dialysis; Epidemiology; Female; Health insurance; Health risk assessment; Hemodialysis; Hospitalization; Humans; Incidence; Male; Medicine and Health Sciences; Middle Aged; Mortality; Multiple myeloma; Multiple Myeloma - epidemiology; Multiple Myeloma - mortality; Patient outcomes; Patients; People and Places; Population Surveillance; Prevalence; Prevalence studies (Epidemiology); Registries; Risk; Risk Factors; Socioeconomic Factors; Taiwan - epidemiology
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0167227

In this retrospective cohort study based in Taiwan, we reported the current epidemiology of patients with multiple myeloma and analyzed the factors affecting mortality. We identified 7285 patients with newly diagnosed multiple myeloma (MM) between 1997 and 2013 in Taiwan. Privileges data from the National Health Institute Research Database was used, as it is made readily available to the public in electronic format for research purposes. From 1997 to 2013, the average incidence of MM per 100,000 people was 1.83. The mortality accounted for an average of 0.44 per 100,000 deaths. In all 7285 inpatients with MM, the proportion of male patients was greater than that of female (59.90% vs. 40.10%); the mean age was 68.71 years with the proportion of those >55 years of age was 85.11%; and the proportion of a catastrophic illness was 66.51%. The death risk of the inpatient dialysis group was 3.044 times that of patients without dialysis (P 55 years, the risk of in-hospital death was 1.511 times more than that in those aged ≤55 years (P