Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle

The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. Nellore steers were finished in feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records of tenderness and 1,873 marbling rec...

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Published in:PloS one 2016-06, Vol.11 (6), p.e0157845-e0157845
Main Authors: Magalhães, Ana F B, de Camargo, Gregório M F, Fernandes, Junior, Gerardo A, Gordo, Daniel G M, Tonussi, Rafael L, Costa, Raphael B, Espigolan, Rafael, Silva, Rafael M de O, Bresolin, Tiago, de Andrade, Willian B F, Takada, Luciana, Feitosa, Fabieli L B, Baldi, Fernando, Carvalheiro, Roberto, Chardulo, Luis A L, de Albuquerque, Lucia G
Format: Article
Language:English
Subjects:
Abattoirs
Analysis
Animals
Beef
Beef cattle
Biology and Life Sciences
Bos taurus
Bos taurus indicus
Bovidae
Cattle
Chromosomes
Feedlots
Female
Gene expression
Genes
Genetic diversity
Genetic variance
Genome-wide association studies
Genome-Wide Association Study - methods
Genomes
Genomics
Intensive farming
Lipid metabolism
Male
Meat
Meat quality
Medicine and Health Sciences
Metabolism
Muscles
Mutation
Physiological aspects
Polymorphism, Single Nucleotide
Quality control
Quantitative genetics
Quantitative Trait Loci
Red Meat
Selective Breeding
Single-nucleotide polymorphism
Social Sciences
Studies
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cited_by cdi_FETCH-LOGICAL-c725t-ea80f99c61da5af942f78c7f1a28a0ca187a2eb61927506332952a8c4a69830a3
cites cdi_FETCH-LOGICAL-c725t-ea80f99c61da5af942f78c7f1a28a0ca187a2eb61927506332952a8c4a69830a3
container_end_page e0157845
container_issue 6
container_start_page e0157845
container_title PloS one
container_volume 11
creator Magalhães, Ana F B
de Camargo, Gregório M F
Fernandes, Junior, Gerardo A
Gordo, Daniel G M
Tonussi, Rafael L
Costa, Raphael B
Espigolan, Rafael
Silva, Rafael M de O
Bresolin, Tiago
de Andrade, Willian B F
Takada, Luciana
Feitosa, Fabieli L B
Baldi, Fernando
Carvalheiro, Roberto
Chardulo, Luis A L
de Albuquerque, Lucia G
description The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. Nellore steers were finished in feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records of tenderness and 1,873 marbling records. After quality control, 1,630 animals genotyped for tenderness, 1,633 animals genotyped for marbling, and 369,722 SNPs remained. The results are reported as the proportion of variance explained by windows of 150 adjacent SNPs. Only windows with largest effects were considered. The genomic regions were located on chromosomes 5, 15, 16 and 25 for marbling and on chromosomes 5, 7, 10, 14 and 21 for tenderness. These windows explained 3,89% and 3,80% of the additive genetic variance for marbling and tenderness, respectively. The genes associated with the traits are related to growth, muscle development and lipid metabolism. The study of these genes in Nellore cattle is the first step in the identification of causal mutations that will contribute to the genetic evaluation of the breed.
doi_str_mv 10.1371/journal.pone.0157845
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subjects Abattoirs
Analysis
Animals
Beef
Beef cattle
Biology and Life Sciences
Bos taurus
Bos taurus indicus
Bovidae
Cattle
Chromosomes
Feedlots
Female
Gene expression
Genes
Genetic diversity
Genetic variance
Genome-wide association studies
Genome-Wide Association Study - methods
Genomes
Genomics
Intensive farming
Lipid metabolism
Male
Meat
Meat quality
Medicine and Health Sciences
Metabolism
Muscles
Mutation
Physiological aspects
Polymorphism, Single Nucleotide
Quality control
Quantitative genetics
Quantitative Trait Loci
Red Meat
Selective Breeding
Single-nucleotide polymorphism
Social Sciences
Studies
title Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle
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