Analysis of the causes of recurrence after frontalis suspension using silicone rods for congenital ptosis

• Published in: PloS one 2017-02, Vol.12 (2), p.e0171769-e0171769
• Main Authors: Kim, Chang Yeom, Son, Byeong Jae, Son, Jangyup, Hong, Jongill, Lee, Sang Yeul
• Format: Article
• Language: English
• Subjects: Biocompatible Materials - adverse effects; Biology and Life Sciences; Blepharoptosis; Blepharoptosis - congenital; Blepharoptosis - pathology; Blepharoptosis - surgery; Care and treatment; Child, Preschool; Disintegration; Electron micrographs; Female; Fixation; Genetic aspects; Guardians; Humans; Infant; Male; Materials science; Materials Testing; Medicine; Medicine and Health Sciences; Migration; Neuromuscular diseases; Patients; Pediatrics; Physical Sciences; Prospective Studies; Prostheses and Implants - adverse effects; Recurrence; Recurrence (Disease); Risk factors; Rods; Silicones; Surgery; Synthetic products; Tensile strength
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0171769

Silicone rod is a commonly used synthetic suspension material in frontalis suspension surgery to correct blepharoptosis. The most challenging problem and a decisive drawback of the use of silicone rod is a considerable rate of ptosis recurrence after surgery. We examined patients with recurred ptosis and assessed the physical and micromorphological properties of implanted silicone rods to determine the causative mechanisms of recurred ptosis after frontalis suspension using silicone rod. This is a prospective observational case series of 22 pediatric patients with recurred ptosis after frontalis suspension using silicone rods for congenital ptosis. Implanted silicone rods were observed and removed during the operation for correction of recurred ptosis. The removed silicone rods were physically and micromorphologically evaluated to determine the cause of recurrence. Pretarsal fixation positions migrated upward, whereas suprabrow fixation positions migrated downward during ptosis recurrence. The breaking strength of implanted silicone rods was reduced by approximately 50% during 3 years. Cracks, debris, and loss of homogenous structure with disintegration were observed on scanning electron micrographs of implanted silicone rods in patients with recurred ptosis. Preoperative severe degree of ptosis also contributed to recurred ptosis. Recurrence of ptosis after frontalis suspension using silicone rod was associated with physical changes of implanted silicone rods, including positional migration, weakened tensile strength, and micromorphological changes in combination with patients' characteristics.