The association of dietary vitamin C intake with periodontitis among Korean adults: Results from KNHANES

• Published in: PloS one 2017, Vol.12 (5), p.e0177074-e0177074
• Main Authors: Lee, Jung-Hoo, Shin, Myung-Seop, Kim, Eun-Jeong, Ahn, Yoo-Been, Kim, Hyun-Duck
• Format: Article
• Language: English
• Subjects: Adult; Adults; Age; Aged; Alcohol; Alcohol Drinking - epidemiology; Alcohol use; Alcoholic beverages; Antioxidants; Arches; Ascorbic acid; Ascorbic Acid - therapeutic use; Audio frequencies; Biology and Life Sciences; Bleeding; Brushing; Calculi; Cardiovascular diseases; Cell activation; Cell differentiation; Chemotaxis; Computer programs; Confidence intervals; Cross-Sectional Studies; Data processing; Dental research; Dentistry; Destruction; Diabetes; Diabetes mellitus; Diabetes Mellitus - epidemiology; Diet; Dietary intake; Differentiation; Disease control; Disease prevention; Drinking behavior; Ear; Fasting; Female; Food; Food composition; Food intake; Gum disease; Health risks; Heart diseases; Humans; Hypercholesterolemia; Hypertension; Incidence; Income; Infections; Inflammation; Information dissemination; Intervention; Inventories; Male; Mathematical analysis; Medicine and Health Sciences; Metabolic disorders; Microflora; Microorganisms; Middle Aged; Nutrient requirements; Nutrients; Nutrition; Nutrition Surveys; Obesity; Obesity - epidemiology; Odds Ratio; Oral hygiene; Oxidative stress; Periodontal Index; Periodontics; Periodontitis; Periodontitis - epidemiology; Periodontitis - prevention & control; Physical sciences; Population studies; Pregnancy; Prevention; Quartiles; Regression analysis; Republic of Korea - epidemiology; Risk factors; Smoking; Smoking - epidemiology; Statistical analysis; Statistical methods; Studies; Teeth; Toothbrushing; Vitamin C; Vitamins - therapeutic use; Young Adult
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0177074

The association of dietary vitamin C (vit C) on periodontitis requires more valid evidence from large representative samples to enable sufficient adjustments. This study aimed to evaluate the association between dietary vit C intake and periodontitis after controlling for various confounders in the representative Korean adult population. A total of 10,930 Korean adults (≥19 years) from the fourth Korean National Health and Nutrition Examination Survey data set were included in this cross-sectional study. Periodontitis was defined as community periodontal index score of 3 or 4. Dietary vit C intake was estimated from a 24-hour dietary record, and categorized into adequate and inadequate according to the Korean Estimated Average Requirement value. Potential confounders included age, sex, income, frequency of tooth brushing, use of floss, dental visit, drinking, smoking, diabetes, hypercholesterolemia, hypertension, and obesity. A multivariable logistic regression analysis and stratified analysis were applied. Those with inadequate dietary vit C intake were more likely by 1.16 times to have periodontitis than those with adequate dietary vit C intake (adjusted odds ratio [aOR] = 1.16, 95% confidence interval = 1.04-1.29). Lowest and middle-low quartile of dietary vit C intake, compared to highest quartile of dietary vit C intake, showed significant association (aOR = 1.28 and 1.22 respectively), which was in a biological-gradient relationship (trend-p