Signification of distal urinary acidification defects in hypocitraturic patients

Hypocitraturia has been associated with metabolic acidosis and mineral disorders. The aim of this study was to investigate the occurrence of urinary acidification defects underlying hypocitraturia. This retrospective observational study included 67 patients (32 men), aged 40.7±15.1 years with hypoci...

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Bibliographic Details
Published in:PloS one 2017-05, Vol.12 (5), p.e0177329-e0177329
Main Authors: Forni Ogna, Valentina, Blanchard, Anne, Vargas-Poussou, Rosa, Ogna, Adam, Baron, Stéphanie, Bertocchio, Jean-Philippe, Prot-Bertoye, Caroline, Nevoux, Jérôme, Dubourg, Julie, Maruani, Gérard, Mendes, Margarida, Garcia-Castaño, Alejandro, Treard, Cyrielle, Lepottier, Nelly, Houillier, Pascal, Courbebaisse, Marie
Format: Article
Language:English
Subjects:
Acid deposition
Acid-base status
Acidification
Acidosis
Acids
Adult
Age
Ammonia
Ammonium
Ammonium chloride
Analysis
Analytical methods
Anthropometry
Autoimmune diseases
Bicarbonates
Biology and Life Sciences
Blood
Bone demineralization
Bone density
Buffers
Calcinosis
Carbon dioxide
Carbonates
Chlorides
Contamination
Creatinine
Crystallization
Deafness
Defects
Demineralization
Excretion
Female
Genetic screening
H+-transporting ATPase
Health aspects
Hearing loss
Humans
Hydrogen ions
Hydrogen-Ion Concentration
Kidney - metabolism
Kidney diseases
Life Sciences
Lithiasis
Male
Medicine and Health Sciences
Metabolism
Middle Aged
Mutation
Observational studies
Patients
Phosphates
Physical Sciences
Potassium Citrate - metabolism
Potassium Citrate - urine
Retrospective Studies
Risk factors
Sjogren's syndrome
Urination disorders
Urine
Young Adult
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Summary:Hypocitraturia has been associated with metabolic acidosis and mineral disorders. The aim of this study was to investigate the occurrence of urinary acidification defects underlying hypocitraturia. This retrospective observational study included 67 patients (32 men), aged 40.7±15.1 years with hypocitraturia (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0177329