Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients

While the association of ethnic group with individual cardiovascular diseases has been studied, little is known about ethnic differences in the initial lifetime presentation of clinical cardiovascular disease in contemporary populations. We studied 1,068,318 people, aged ≥30 years and free from diag...

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Bibliographic Details
Published in:PloS one 2017-06, Vol.12 (6), p.e0178945-e0178945
Main Authors: George, Julie, Mathur, Rohini, Shah, Anoop Dinesh, Pujades-Rodriguez, Mar, Denaxas, Spiros, Smeeth, Liam, Timmis, Adam, Hemingway, Harry
Format: Article
Language:English
Subjects:
Adult
Age
Age of Onset
Aged
Analysis
Angina
Biomarkers
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cerebral infarction
Cohort Studies
Coronary artery disease
Demographic aspects
Diagnosis
Electronic Health Records
Electronic medical records
Electronic records
Epidemiology
Ethnicity
Female
Health care
Health risk assessment
Health risks
Heart
Heart diseases
Heart failure
Hemorrhage
Humans
Male
Medical diagnosis
Medicine and Health Sciences
Middle Aged
Minority & ethnic groups
Mortality
Myocardial infarction
Patients
People and Places
Population Surveillance
Populations
Public health
Registries
Risk Factors
Sex
Social Sciences
Stroke
United Kingdom - epidemiology
Xenografts
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Summary:While the association of ethnic group with individual cardiovascular diseases has been studied, little is known about ethnic differences in the initial lifetime presentation of clinical cardiovascular disease in contemporary populations. We studied 1,068,318 people, aged ≥30 years and free from diagnosed CVD at baseline (90.9% White, 3.6% South Asian and 2.9% Black), using English linked electronic health records covering primary care, hospital admissions, acute coronary syndrome registry and mortality registry (CALIBER platform). During 5.7 years median follow-up between 1997-2010, 95,224 people experienced an incident cardiovascular diagnosis. 69.9% (67.2%-72.4%) of initial presentation in South Asian
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0178945