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Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay

About the Authors: Fábio Brito-Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Marcela de Faria Ferreira Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Luciana Trilles Af...

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Published in:PLoS neglected tropical diseases 2017-05, Vol.11 (5), p.e0005304-e0005304
Main Authors: Brito-Santos, Fábio, Ferreira, Marcela de Faria, Trilles, Luciana, Muniz, Mauro de Medeiros, Veloso Dos Santos, Valdiléa Gonçalves, Carvalho-Costa, Filipe Anibal, Meyer, Wieland, Wanke, Bodo, Lazéra, Márcia Dos Santos
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container_title PLoS neglected tropical diseases
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creator Brito-Santos, Fábio
Ferreira, Marcela de Faria
Trilles, Luciana
Muniz, Mauro de Medeiros
Veloso Dos Santos, Valdiléa Gonçalves
Carvalho-Costa, Filipe Anibal
Meyer, Wieland
Wanke, Bodo
Lazéra, Márcia Dos Santos
description About the Authors: Fábio Brito-Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Marcela de Faria Ferreira Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Luciana Trilles Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Mauro de Medeiros Muniz Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Valdiléa Gonçalves Veloso dos Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Filipe Anibal Carvalho-Costa Affiliation: Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil Wieland Meyer Affiliations National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil, Centre for Infectious Diseases and Microbiology, Sydney Medical School-Westmead Hospital, Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Westmead Institute for Medical Research, Sydney, New South Wales, Australia Bodo Wanke Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Márcia dos Santos Lazéra * E-mail: marcia.lazera@ini.fiocruz.br Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil ORCID http://orcid.org/0000-0002-1620-4118Citation: Brito-Santos F, Ferreira MdF, Trilles L, Muniz MdM, Veloso dos Santos VG, Carvalho-Costa FA, et al. Overview A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the high lethality rate due to cryptococcosis. A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the...
doi_str_mv 10.1371/journal.pntd.0005304
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C.</contributor><creatorcontrib>Brito-Santos, Fábio ; Ferreira, Marcela de Faria ; Trilles, Luciana ; Muniz, Mauro de Medeiros ; Veloso Dos Santos, Valdiléa Gonçalves ; Carvalho-Costa, Filipe Anibal ; Meyer, Wieland ; Wanke, Bodo ; Lazéra, Márcia Dos Santos ; Small, Pamela L. C.</creatorcontrib><description>About the Authors: Fábio Brito-Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Marcela de Faria Ferreira Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Luciana Trilles Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Mauro de Medeiros Muniz Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Valdiléa Gonçalves Veloso dos Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Filipe Anibal Carvalho-Costa Affiliation: Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil Wieland Meyer Affiliations National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil, Centre for Infectious Diseases and Microbiology, Sydney Medical School-Westmead Hospital, Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Westmead Institute for Medical Research, Sydney, New South Wales, Australia Bodo Wanke Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Márcia dos Santos Lazéra * E-mail: marcia.lazera@ini.fiocruz.br Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil ORCID http://orcid.org/0000-0002-1620-4118Citation: Brito-Santos F, Ferreira MdF, Trilles L, Muniz MdM, Veloso dos Santos VG, Carvalho-Costa FA, et al. Overview A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the high lethality rate due to cryptococcosis. A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the...</description><identifier>ISSN: 1935-2735</identifier><identifier>ISSN: 1935-2727</identifier><identifier>EISSN: 1935-2735</identifier><identifier>DOI: 10.1371/journal.pntd.0005304</identifier><identifier>PMID: 28493865</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>AIDS-Related Opportunistic Infections - diagnosis ; AIDS-Related Opportunistic Infections - urine ; Analysis ; Antigens ; Antigens, Fungal - immunology ; Antigens, Fungal - urine ; Assaying ; Biology and Life Sciences ; Biosecurity ; Cryptococcosis ; Cryptococcosis - complications ; Cryptococcosis - diagnosis ; Cryptococcosis - urine ; Cryptococcus neoformans - metabolism ; Diagnostic tests ; From Innovation to Application ; Fungal infections ; Fungi ; Heating ; HIV Infections - complications ; Hot Temperature ; Humans ; Infectious diseases ; Medical research ; Medicine and Health Sciences ; Microbiology ; Point-of-Care Systems ; Research and Analysis Methods ; Sensitivity and Specificity ; Specificity ; Studies ; Testing ; Tropical diseases ; Urinalysis ; Urinalysis - methods ; Urine ; Vector-borne diseases</subject><ispartof>PLoS neglected tropical diseases, 2017-05, Vol.11 (5), p.e0005304-e0005304</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Brito-Santos F, Ferreira MdF, Trilles L, Muniz MdM, Veloso dos Santos VG, Carvalho-Costa FA, et al. (2017) Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay. PLoS Negl Trop Dis 11(5): e0005304. https://doi.org/10.1371/journal.pntd.0005304</rights><rights>2017 Brito-Santos et al 2017 Brito-Santos et al</rights><rights>2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Brito-Santos F, Ferreira MdF, Trilles L, Muniz MdM, Veloso dos Santos VG, Carvalho-Costa FA, et al. (2017) Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay. 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Fisheries Abstracts (ASFA) 1: Biological Sciences &amp; Living Resources</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) 3: Aquatic Pollution &amp; Environmental Quality</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) Professional</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PLoS neglected tropical diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brito-Santos, Fábio</au><au>Ferreira, Marcela de Faria</au><au>Trilles, Luciana</au><au>Muniz, Mauro de Medeiros</au><au>Veloso Dos Santos, Valdiléa Gonçalves</au><au>Carvalho-Costa, Filipe Anibal</au><au>Meyer, Wieland</au><au>Wanke, Bodo</au><au>Lazéra, Márcia Dos Santos</au><au>Small, Pamela L. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay</atitle><jtitle>PLoS neglected tropical diseases</jtitle><addtitle>PLoS Negl Trop Dis</addtitle><date>2017-05-11</date><risdate>2017</risdate><volume>11</volume><issue>5</issue><spage>e0005304</spage><epage>e0005304</epage><pages>e0005304-e0005304</pages><issn>1935-2735</issn><issn>1935-2727</issn><eissn>1935-2735</eissn><abstract>About the Authors: Fábio Brito-Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Marcela de Faria Ferreira Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Luciana Trilles Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Mauro de Medeiros Muniz Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Valdiléa Gonçalves Veloso dos Santos Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Filipe Anibal Carvalho-Costa Affiliation: Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil Wieland Meyer Affiliations National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil, Centre for Infectious Diseases and Microbiology, Sydney Medical School-Westmead Hospital, Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Westmead Institute for Medical Research, Sydney, New South Wales, Australia Bodo Wanke Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil Márcia dos Santos Lazéra * E-mail: marcia.lazera@ini.fiocruz.br Affiliation: National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil ORCID http://orcid.org/0000-0002-1620-4118Citation: Brito-Santos F, Ferreira MdF, Trilles L, Muniz MdM, Veloso dos Santos VG, Carvalho-Costa FA, et al. Overview A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the high lethality rate due to cryptococcosis. A delay in laboratory diagnosis is related to sequelae and death. [...]early diagnosis is the key to decrease the...</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28493865</pmid><doi>10.1371/journal.pntd.0005304</doi><orcidid>https://orcid.org/0000-0002-1620-4118</orcidid><oa>free_for_read</oa></addata></record>
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identifier ISSN: 1935-2735
ispartof PLoS neglected tropical diseases, 2017-05, Vol.11 (5), p.e0005304-e0005304
issn 1935-2735
1935-2727
1935-2735
language eng
recordid cdi_plos_journals_1910461897
source Open Access: PubMed Central; Publicly Available Content Database
subjects AIDS-Related Opportunistic Infections - diagnosis
AIDS-Related Opportunistic Infections - urine
Analysis
Antigens
Antigens, Fungal - immunology
Antigens, Fungal - urine
Assaying
Biology and Life Sciences
Biosecurity
Cryptococcosis
Cryptococcosis - complications
Cryptococcosis - diagnosis
Cryptococcosis - urine
Cryptococcus neoformans - metabolism
Diagnostic tests
From Innovation to Application
Fungal infections
Fungi
Heating
HIV Infections - complications
Hot Temperature
Humans
Infectious diseases
Medical research
Medicine and Health Sciences
Microbiology
Point-of-Care Systems
Research and Analysis Methods
Sensitivity and Specificity
Specificity
Studies
Testing
Tropical diseases
Urinalysis
Urinalysis - methods
Urine
Vector-borne diseases
title Preheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay
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