Distribution and associations of intraocular pressure in 7- and 12-year-old Chinese children: The Anyang Childhood Eye Study

• Published in: PloS one 2017-08, Vol.12 (8), p.e0181922-e0181922
• Main Authors: Li, Shuning, Li, Shi-Ming, Wang, Xiao-Lei, Kang, Meng-Tian, Liu, Luo-Ru, Li, He, Wei, Shi-Fei, Ran, An-Ran, Zhan, Siyan, Thomas, Ravi, Wang, Ningli
• Format: Article
• Language: English
• Subjects: Adolescents; Age; Anterior chamber; Biology and Life Sciences; Blood pressure; Body mass; Body mass index; Child; Children; China - epidemiology; China - ethnology; Cornea; Cornea - pathology; Cornea - physiopathology; Delivery (Childbirth); Demographic aspects; Ethnicity; Eye; Female; Glaucoma; Health care; Humans; Intraocular Pressure; Male; Medicine and Health Sciences; Myopia; Myopia - epidemiology; People and Places; Physiological aspects; Population; Public Health Surveillance; Reading; Refraction; Regression analysis; Regression coefficients; Science; Src protein; Stress concentration
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0181922

To report the intraocular pressure (IOP) and its association with myopia and other factors in 7 and 12-year-old Chinese children. All children participating in the Anyang Childhood Eye Study underwent non-contact tonometry as well as measurement of central corneal thickness (CCT), axial length, cycloplegic auto-refraction, blood pressure, height and weight. A questionnaire was used to collect other relevant information. Univariable and multivariable analysis were performed to determine the associations of IOP. A total of 2760 7-year-old children (95.4%) and 2198 12-year-old children (97.0%) were included. The mean IOP was 13.5±3.1 mmHg in the younger cohort and 15.8±3.5 mmHg in older children (P