Does inhalation injury predict mortality in burns patients or require redefinition?

Inhalation injury is known to be an important factor in predicting mortality in burns patients. However, the diagnosis is complicated by the heterogeneous presentation and inability to determine the severity of inhalation injury. The purpose of this study was to identify clinical features of inhalat...

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Bibliographic Details
Published in:PloS one 2017-09, Vol.12 (9), p.e0185195-e0185195
Main Authors: Kim, Youngmin, Kym, Dohern, Hur, Jun, Yoon, Jaechul, Yim, Haejun, Cho, Yong Suk, Chun, Wook
Format: Article
Language:English
Subjects:
Age
Analysis
Biology and Life Sciences
Blood pressure
Burns
Burns (injuries)
Burns - complications
Burns - mortality
Burns - physiopathology
Carboxyhemoglobin
Complications and side effects
Demography
Diagnosis
Emergency services
Female
Humans
Inhalation
Injuries
Logistic Models
Male
Mechanical ventilation
Medicine and Health Sciences
Middle Aged
Mortality
Multivariate Analysis
Oxygen - metabolism
Patients
Physical Sciences
Prognosis
Regression analysis
Research and Analysis Methods
Respiration
Respiratory Function Tests
Risk factors
Smoke inhalation
Smoke Inhalation Injury - complications
Smoke Inhalation Injury - mortality
Smoke Inhalation Injury - physiopathology
South Korea
Statistical analysis
Surface area
Survival Analysis
Survivors
Ventilation
Ventilators
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Summary:Inhalation injury is known to be an important factor in predicting mortality in burns patients. However, the diagnosis is complicated by the heterogeneous presentation and inability to determine the severity of inhalation injury. The purpose of this study was to identify clinical features of inhalation injury that affect mortality and the values that could predict the outcome more precisely in burns patients with inhalation injury. This retrospective observational study included 676 burns patients who were over 18 years of age and hospitalized in the Burns Intensive Care Unit between January 2012 and December 2015. We analyzed variables that are already known to be prognostic factors (age, percentage of total body surface area (%TBSA) burned, and inhalation injury) and factors associated with inhalation injury (carboxyhemoglobin and PaO2/FiO2 [PF] ratio) by univariate and multivariate logistic regression. Age group (odds ratio [OR] 1.069, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0185195