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Modification of hydrophilic and hydrophobic surfaces using an ionic-complementary peptide

Ionic-complementary peptides are novel nano-biomaterials with a variety of biomedical applications including potential biosurface engineering. This study presents evidence that a model ionic-complementary peptide EAK16-II is capable of assembling/coating on hydrophilic mica as well as hydrophobic hi...

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Bibliographic Details
Published in:PloS one 2007-12, Vol.2 (12), p.e1325
Main Authors: Yang, Hong, Fung, Shan-Yu, Pritzker, Mark, Chen, P
Format: Article
Language:English
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Summary:Ionic-complementary peptides are novel nano-biomaterials with a variety of biomedical applications including potential biosurface engineering. This study presents evidence that a model ionic-complementary peptide EAK16-II is capable of assembling/coating on hydrophilic mica as well as hydrophobic highly ordered pyrolytic graphite (HOPG) surfaces with different nano-patterns. EAK16-II forms randomly oriented nanofibers or nanofiber networks on mica, while ordered nanofibers parallel or oriented 60 degrees or 120 degrees to each other on HOPG, reflecting the crystallographic symmetry of graphite (0001). The density of coated nanofibers on both surfaces can be controlled by adjusting the peptide concentration and the contact time of the peptide solution with the surface. The coated EAK16-II nanofibers alter the wettability of the two surfaces differently: the water contact angle of bare mica surface is measured to be
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0001325