Detection of spontaneous pulse using the acceleration signals acquired from CPR feedback sensor in a porcine model of cardiac arrest

Reliable detection of return of spontaneous circulation with minimal interruptions of chest compressions is part of high-quality cardiopulmonary resuscitation (CPR) and routinely done by checking pulsation of carotid arteries. However, manual palpation was time-consuming and unreliable even if perfo...

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Bibliographic Details
Published in:PloS one 2017-12, Vol.12 (12), p.e0189217-e0189217
Main Authors: Wei, Liang, Chen, Gang, Yang, Zhengfei, Yu, Tao, Quan, Weilun, Li, Yongqin
Format: Article
Language:English
Subjects:
Acceleration
Accelerometers
Arteries
Automation
Biology and Life Sciences
Biomedical engineering
Blood pressure
Cardiac arrest
Cardiopulmonary resuscitation
Carotid arteries
Carotid artery
Catheters
Chest
Compression
Correlation
Correlation coefficient
Correlation coefficients
CPR
Defibrillators
EKG
Electrophysiology
Engineering and Technology
Feedback
Heart
Heart diseases
Hogs
Laboratory animals
Medical research
Medicine and Health Sciences
Methods
Research and Analysis Methods
Resuscitation
Rhythm
Segments
Studies
Swine
Waveforms
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Summary:Reliable detection of return of spontaneous circulation with minimal interruptions of chest compressions is part of high-quality cardiopulmonary resuscitation (CPR) and routinely done by checking pulsation of carotid arteries. However, manual palpation was time-consuming and unreliable even if performed by expert clinicians. Therefore, automated accurate pulse detection with minimal interruptions of chest compression is highly desirable during cardiac arrest especially in out-of-hospital settings. To investigate whether the acceleration (ACC) signals acquired from accelerometer-based CPR feedback sensor can be used to distinguish perfusing rhythm (PR) from pulseless electrical activity (PEA) in a porcine model of cardiac arrest. Cardiac arrest was induced in 49 male adult pigs. ECG, arterial blood pressure (ABP) and ACC waveforms were simultaneously recorded during CPR. 3-second segments containing compression-free signals during chest compression pauses were extracted and only those segments with organized rhythm were used for analysis. PR was defined as systolic arterial pressure >60 mmHg and pulse pressure >10 mmHg, while PEA was defined as an organized rhythm that does not meet the above criteria for PR. Peak correlation coefficient (CCp) of the cross-correlation function between pre-processed ECG and ACC, was used to discriminate PR and PEA. 63 PR and 153 PEA were identified from the total of 1025 extracted segments. CCp was significantly higher for PR as compared to PEA (0.440±0.176 vs. 0.067±0.042, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0189217