Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam

HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. We used cro...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2018-01, Vol.13 (1), p.e0191548-e0191548
Main Authors: Levintow, Sara N, Pence, Brian W, Ha, Tran Viet, Minh, Nguyen Le, Sripaipan, Teerada, Latkin, Carl A, Vu, Pham The, Quan, Vu Minh, Frangakis, Constantine, Go, Vivian F
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adult
AIDS
Alcohol use
Alcohols
Analysis
Biology and Life Sciences
Cigarette smoking
Confidence intervals
Demographics
Depression (Mood disorder)
Depression - complications
Depression - physiopathology
Development and progression
Dosage and administration
Drug abuse
Drug dependence
Drug use
Drugs
Epidemiology
HIV
HIV Infections - complications
Human immunodeficiency virus
Humans
Male
Mathematical models
Medicine and Health Sciences
Mental depression
Middle Aged
Overdose
People and Places
Physical Sciences
Prevalence
Preventive medicine
Psychological aspects
Quality of life
Risk factors
Risk taking
Sexual behavior
Sexually transmitted diseases
Smoking
Social interactions
Statistical analysis
STD
Studies
Vietnam - epidemiology
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3
cites cdi_FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3
container_end_page e0191548
container_issue 1
container_start_page e0191548
container_title PloS one
container_volume 13
creator Levintow, Sara N
Pence, Brian W
Ha, Tran Viet
Minh, Nguyen Le
Sripaipan, Teerada
Latkin, Carl A
Vu, Pham The
Quan, Vu Minh
Frangakis, Constantine
Go, Vivian F
description HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. We used cross-sectional data from PWID in a randomized controlled trial of an intervention to reduce high-risk injecting and sexual behaviors in Thai Nguyen from 2009-2013. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D). We used logistic regression to assess demographic, clinical, and psychosocial predictors of severe depressive symptoms (CES-D≥23) with prevalence odds ratios (POR) and 95% confidence intervals (CI). The prevalence of severe depressive symptoms (CES-D≥23) was 44%. 25% of participants had mild to moderate depressive symptoms (16≤CES-D
doi_str_mv 10.1371/journal.pone.0191548
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1990920535</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A524690795</galeid><doaj_id>oai_doaj_org_article_bd390ea74f804b448236344085a03718</doaj_id><sourcerecordid>A524690795</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3</originalsourceid><addsrcrecordid>eNqNk01v1DAQhiMEoqXwDxBEQkJw2MWOP2JfkKoK6EqVivjYq-U4zq5XiR1sZ6H_HqebVhvUA_LBnvEz79hjT5a9hGAJUQk_7NzgrWyXvbN6CSCHBLNH2SnkqFjQAqDHR-uT7FkIOwAIYpQ-zU4KjijmBTvN1Fev97LVVulc2jrvva6Nis6H3DV5rZMdgtnrPNx0fXRdyGXn7Ca_XK0XvQsmjnudtvnvrcuN3WkV89oPm5CMfG10tLJ7nj1pZBv0i2k-y35-_vTj4nJxdf1ldXF-tVCUF3FRUgKYkgBwBSvNES5KyhgCFZOEVTWpFKEAlk1RQ0oaghBuZE0rjFSDJMYSnWWvD7p964KY6hME5BzwIt2dJGJ1IGond6L3ppP-RjhpxK3D-Y2QPhrValHViAMtS9wwgCuMWYEowhgwIkEqP0taH6dsQ9XpWmkbvWxnovMda7Zi4_aClAxhUCaBd5OAd78GHaLoTFC6baXVbrg9N4QMFHxE3_yDPny7idqkBxXGNi7lVaOoOCcFphyUfKSWD1Bp1LozKn2mxiT_LOD9LCAxUf-JGzmEIFbfv_0_e72es2-P2K2WbdwG1w7ROBvmID6AyrsQvG7uiwyBGHvhrhpi7AUx9UIKe3X8QPdBd58f_QWWTwMm</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1990920535</pqid></control><display><type>article</type><title>Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PubMed Central Free</source><creator>Levintow, Sara N ; Pence, Brian W ; Ha, Tran Viet ; Minh, Nguyen Le ; Sripaipan, Teerada ; Latkin, Carl A ; Vu, Pham The ; Quan, Vu Minh ; Frangakis, Constantine ; Go, Vivian F</creator><contributor>Moitra, Ethan</contributor><creatorcontrib>Levintow, Sara N ; Pence, Brian W ; Ha, Tran Viet ; Minh, Nguyen Le ; Sripaipan, Teerada ; Latkin, Carl A ; Vu, Pham The ; Quan, Vu Minh ; Frangakis, Constantine ; Go, Vivian F ; Moitra, Ethan</creatorcontrib><description>HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. We used cross-sectional data from PWID in a randomized controlled trial of an intervention to reduce high-risk injecting and sexual behaviors in Thai Nguyen from 2009-2013. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D). We used logistic regression to assess demographic, clinical, and psychosocial predictors of severe depressive symptoms (CES-D≥23) with prevalence odds ratios (POR) and 95% confidence intervals (CI). The prevalence of severe depressive symptoms (CES-D≥23) was 44%. 25% of participants had mild to moderate depressive symptoms (16≤CES-D&lt;23), and 31% experienced no depressive symptoms (CES-D&lt;16). Not being married, self-rated poor health, greater frequency of injection drug use, history of overdose, no alcohol use, and daily cigarette smoking were positively associated with severe depressive symptoms in unadjusted models and remained predictive in a multivariable model. The strongest predictors of depressive symptoms were self-reported poor health (POR = 2.94, 95% CI: 1.82, 4.76), no current alcohol use (POR = 2.35, 95% CI: 1.47, 3.77), and not currently married or cohabitating (POR = 2.21, 95% CI = 1.40, 3.47). Severe depressive symptoms were common among HIV-positive PWID in Thai Nguyen and were strongly associated with demographic, clinical, and psychosocial factors. Interventions that promote social support from family and reduce drug dependence may particularly benefit PWID experiencing severe depressive symptoms. Greater recognition and treatment of depressive symptoms has the potential to enhance quality of life and improve HIV clinical outcomes for PWID.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0191548</identifier><identifier>PMID: 29364928</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acquired immune deficiency syndrome ; Adult ; AIDS ; Alcohol use ; Alcohols ; Analysis ; Biology and Life Sciences ; Cigarette smoking ; Confidence intervals ; Demographics ; Depression (Mood disorder) ; Depression - complications ; Depression - physiopathology ; Development and progression ; Dosage and administration ; Drug abuse ; Drug dependence ; Drug use ; Drugs ; Epidemiology ; HIV ; HIV Infections - complications ; Human immunodeficiency virus ; Humans ; Male ; Mathematical models ; Medicine and Health Sciences ; Mental depression ; Middle Aged ; Overdose ; People and Places ; Physical Sciences ; Prevalence ; Preventive medicine ; Psychological aspects ; Quality of life ; Risk factors ; Risk taking ; Sexual behavior ; Sexually transmitted diseases ; Smoking ; Social interactions ; Statistical analysis ; STD ; Studies ; Vietnam - epidemiology ; Young Adult</subject><ispartof>PloS one, 2018-01, Vol.13 (1), p.e0191548-e0191548</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Levintow et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Levintow et al 2018 Levintow et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3</citedby><cites>FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3</cites><orcidid>0000-0001-5558-526X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1990920535/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1990920535?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29364928$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Moitra, Ethan</contributor><creatorcontrib>Levintow, Sara N</creatorcontrib><creatorcontrib>Pence, Brian W</creatorcontrib><creatorcontrib>Ha, Tran Viet</creatorcontrib><creatorcontrib>Minh, Nguyen Le</creatorcontrib><creatorcontrib>Sripaipan, Teerada</creatorcontrib><creatorcontrib>Latkin, Carl A</creatorcontrib><creatorcontrib>Vu, Pham The</creatorcontrib><creatorcontrib>Quan, Vu Minh</creatorcontrib><creatorcontrib>Frangakis, Constantine</creatorcontrib><creatorcontrib>Go, Vivian F</creatorcontrib><title>Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. We used cross-sectional data from PWID in a randomized controlled trial of an intervention to reduce high-risk injecting and sexual behaviors in Thai Nguyen from 2009-2013. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D). We used logistic regression to assess demographic, clinical, and psychosocial predictors of severe depressive symptoms (CES-D≥23) with prevalence odds ratios (POR) and 95% confidence intervals (CI). The prevalence of severe depressive symptoms (CES-D≥23) was 44%. 25% of participants had mild to moderate depressive symptoms (16≤CES-D&lt;23), and 31% experienced no depressive symptoms (CES-D&lt;16). Not being married, self-rated poor health, greater frequency of injection drug use, history of overdose, no alcohol use, and daily cigarette smoking were positively associated with severe depressive symptoms in unadjusted models and remained predictive in a multivariable model. The strongest predictors of depressive symptoms were self-reported poor health (POR = 2.94, 95% CI: 1.82, 4.76), no current alcohol use (POR = 2.35, 95% CI: 1.47, 3.77), and not currently married or cohabitating (POR = 2.21, 95% CI = 1.40, 3.47). Severe depressive symptoms were common among HIV-positive PWID in Thai Nguyen and were strongly associated with demographic, clinical, and psychosocial factors. Interventions that promote social support from family and reduce drug dependence may particularly benefit PWID experiencing severe depressive symptoms. Greater recognition and treatment of depressive symptoms has the potential to enhance quality of life and improve HIV clinical outcomes for PWID.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adult</subject><subject>AIDS</subject><subject>Alcohol use</subject><subject>Alcohols</subject><subject>Analysis</subject><subject>Biology and Life Sciences</subject><subject>Cigarette smoking</subject><subject>Confidence intervals</subject><subject>Demographics</subject><subject>Depression (Mood disorder)</subject><subject>Depression - complications</subject><subject>Depression - physiopathology</subject><subject>Development and progression</subject><subject>Dosage and administration</subject><subject>Drug abuse</subject><subject>Drug dependence</subject><subject>Drug use</subject><subject>Drugs</subject><subject>Epidemiology</subject><subject>HIV</subject><subject>HIV Infections - complications</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Male</subject><subject>Mathematical models</subject><subject>Medicine and Health Sciences</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Overdose</subject><subject>People and Places</subject><subject>Physical Sciences</subject><subject>Prevalence</subject><subject>Preventive medicine</subject><subject>Psychological aspects</subject><subject>Quality of life</subject><subject>Risk factors</subject><subject>Risk taking</subject><subject>Sexual behavior</subject><subject>Sexually transmitted diseases</subject><subject>Smoking</subject><subject>Social interactions</subject><subject>Statistical analysis</subject><subject>STD</subject><subject>Studies</subject><subject>Vietnam - epidemiology</subject><subject>Young Adult</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNk01v1DAQhiMEoqXwDxBEQkJw2MWOP2JfkKoK6EqVivjYq-U4zq5XiR1sZ6H_HqebVhvUA_LBnvEz79hjT5a9hGAJUQk_7NzgrWyXvbN6CSCHBLNH2SnkqFjQAqDHR-uT7FkIOwAIYpQ-zU4KjijmBTvN1Fev97LVVulc2jrvva6Nis6H3DV5rZMdgtnrPNx0fXRdyGXn7Ca_XK0XvQsmjnudtvnvrcuN3WkV89oPm5CMfG10tLJ7nj1pZBv0i2k-y35-_vTj4nJxdf1ldXF-tVCUF3FRUgKYkgBwBSvNES5KyhgCFZOEVTWpFKEAlk1RQ0oaghBuZE0rjFSDJMYSnWWvD7p964KY6hME5BzwIt2dJGJ1IGond6L3ppP-RjhpxK3D-Y2QPhrValHViAMtS9wwgCuMWYEowhgwIkEqP0taH6dsQ9XpWmkbvWxnovMda7Zi4_aClAxhUCaBd5OAd78GHaLoTFC6baXVbrg9N4QMFHxE3_yDPny7idqkBxXGNi7lVaOoOCcFphyUfKSWD1Bp1LozKn2mxiT_LOD9LCAxUf-JGzmEIFbfv_0_e72es2-P2K2WbdwG1w7ROBvmID6AyrsQvG7uiwyBGHvhrhpi7AUx9UIKe3X8QPdBd58f_QWWTwMm</recordid><startdate>20180124</startdate><enddate>20180124</enddate><creator>Levintow, Sara N</creator><creator>Pence, Brian W</creator><creator>Ha, Tran Viet</creator><creator>Minh, Nguyen Le</creator><creator>Sripaipan, Teerada</creator><creator>Latkin, Carl A</creator><creator>Vu, Pham The</creator><creator>Quan, Vu Minh</creator><creator>Frangakis, Constantine</creator><creator>Go, Vivian F</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5558-526X</orcidid></search><sort><creationdate>20180124</creationdate><title>Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam</title><author>Levintow, Sara N ; Pence, Brian W ; Ha, Tran Viet ; Minh, Nguyen Le ; Sripaipan, Teerada ; Latkin, Carl A ; Vu, Pham The ; Quan, Vu Minh ; Frangakis, Constantine ; Go, Vivian F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Adult</topic><topic>AIDS</topic><topic>Alcohol use</topic><topic>Alcohols</topic><topic>Analysis</topic><topic>Biology and Life Sciences</topic><topic>Cigarette smoking</topic><topic>Confidence intervals</topic><topic>Demographics</topic><topic>Depression (Mood disorder)</topic><topic>Depression - complications</topic><topic>Depression - physiopathology</topic><topic>Development and progression</topic><topic>Dosage and administration</topic><topic>Drug abuse</topic><topic>Drug dependence</topic><topic>Drug use</topic><topic>Drugs</topic><topic>Epidemiology</topic><topic>HIV</topic><topic>HIV Infections - complications</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Male</topic><topic>Mathematical models</topic><topic>Medicine and Health Sciences</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Overdose</topic><topic>People and Places</topic><topic>Physical Sciences</topic><topic>Prevalence</topic><topic>Preventive medicine</topic><topic>Psychological aspects</topic><topic>Quality of life</topic><topic>Risk factors</topic><topic>Risk taking</topic><topic>Sexual behavior</topic><topic>Sexually transmitted diseases</topic><topic>Smoking</topic><topic>Social interactions</topic><topic>Statistical analysis</topic><topic>STD</topic><topic>Studies</topic><topic>Vietnam - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Levintow, Sara N</creatorcontrib><creatorcontrib>Pence, Brian W</creatorcontrib><creatorcontrib>Ha, Tran Viet</creatorcontrib><creatorcontrib>Minh, Nguyen Le</creatorcontrib><creatorcontrib>Sripaipan, Teerada</creatorcontrib><creatorcontrib>Latkin, Carl A</creatorcontrib><creatorcontrib>Vu, Pham The</creatorcontrib><creatorcontrib>Quan, Vu Minh</creatorcontrib><creatorcontrib>Frangakis, Constantine</creatorcontrib><creatorcontrib>Go, Vivian F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Science in Context</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Agriculture &amp; Environmental Science Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>https://resources.nclive.org/materials</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Meteorological &amp; Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>ProQuest Engineering Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest advanced technologies &amp; aerospace journals</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levintow, Sara N</au><au>Pence, Brian W</au><au>Ha, Tran Viet</au><au>Minh, Nguyen Le</au><au>Sripaipan, Teerada</au><au>Latkin, Carl A</au><au>Vu, Pham The</au><au>Quan, Vu Minh</au><au>Frangakis, Constantine</au><au>Go, Vivian F</au><au>Moitra, Ethan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-01-24</date><risdate>2018</risdate><volume>13</volume><issue>1</issue><spage>e0191548</spage><epage>e0191548</epage><pages>e0191548-e0191548</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. We used cross-sectional data from PWID in a randomized controlled trial of an intervention to reduce high-risk injecting and sexual behaviors in Thai Nguyen from 2009-2013. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D). We used logistic regression to assess demographic, clinical, and psychosocial predictors of severe depressive symptoms (CES-D≥23) with prevalence odds ratios (POR) and 95% confidence intervals (CI). The prevalence of severe depressive symptoms (CES-D≥23) was 44%. 25% of participants had mild to moderate depressive symptoms (16≤CES-D&lt;23), and 31% experienced no depressive symptoms (CES-D&lt;16). Not being married, self-rated poor health, greater frequency of injection drug use, history of overdose, no alcohol use, and daily cigarette smoking were positively associated with severe depressive symptoms in unadjusted models and remained predictive in a multivariable model. The strongest predictors of depressive symptoms were self-reported poor health (POR = 2.94, 95% CI: 1.82, 4.76), no current alcohol use (POR = 2.35, 95% CI: 1.47, 3.77), and not currently married or cohabitating (POR = 2.21, 95% CI = 1.40, 3.47). Severe depressive symptoms were common among HIV-positive PWID in Thai Nguyen and were strongly associated with demographic, clinical, and psychosocial factors. Interventions that promote social support from family and reduce drug dependence may particularly benefit PWID experiencing severe depressive symptoms. Greater recognition and treatment of depressive symptoms has the potential to enhance quality of life and improve HIV clinical outcomes for PWID.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29364928</pmid><doi>10.1371/journal.pone.0191548</doi><tpages>e0191548</tpages><orcidid>https://orcid.org/0000-0001-5558-526X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1932-6203
ispartof PloS one, 2018-01, Vol.13 (1), p.e0191548-e0191548
issn 1932-6203
1932-6203
language eng
recordid cdi_plos_journals_1990920535
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central Free
subjects Acquired immune deficiency syndrome
Adult
AIDS
Alcohol use
Alcohols
Analysis
Biology and Life Sciences
Cigarette smoking
Confidence intervals
Demographics
Depression (Mood disorder)
Depression - complications
Depression - physiopathology
Development and progression
Dosage and administration
Drug abuse
Drug dependence
Drug use
Drugs
Epidemiology
HIV
HIV Infections - complications
Human immunodeficiency virus
Humans
Male
Mathematical models
Medicine and Health Sciences
Mental depression
Middle Aged
Overdose
People and Places
Physical Sciences
Prevalence
Preventive medicine
Psychological aspects
Quality of life
Risk factors
Risk taking
Sexual behavior
Sexually transmitted diseases
Smoking
Social interactions
Statistical analysis
STD
Studies
Vietnam - epidemiology
Young Adult
title Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T21%3A15%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20and%20predictors%20of%20depressive%20symptoms%20among%20HIV-positive%20men%20who%20inject%20drugs%20in%20Vietnam&rft.jtitle=PloS%20one&rft.au=Levintow,%20Sara%20N&rft.date=2018-01-24&rft.volume=13&rft.issue=1&rft.spage=e0191548&rft.epage=e0191548&rft.pages=e0191548-e0191548&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0191548&rft_dat=%3Cgale_plos_%3EA524690795%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c692t-76508ca009c1be9342768830b8a58bd5bc56017f2d165f5334fad6b43cf3a44a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1990920535&rft_id=info:pmid/29364928&rft_galeid=A524690795&rfr_iscdi=true