Weight loss from 20 years of age is associated with cognitive impairment in middle-aged and elderly individuals

Few empirical studies have been conducted to identify modifiable factors that may affect cognitive impairment in Japanese individuals. The present study aimed to clarify whether body mass and lifestyle are associated with cognitive impairment in Japanese middle-aged and elderly individuals. Subjects...

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Bibliographic Details
Published in:PloS one 2017-10, Vol.12 (10), p.e0185960-e0185960
Main Authors: Kitamura, Kaori, Watanabe, Yumi, Nakamura, Kazutoshi, Takahashi, Akemi, Takachi, Ribeka, Oshiki, Rieko, Kobayashi, Ryosaku, Saito, Toshiko, Tsugane, Shoichiro, Sasaki, Ayako
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Alcohol
Alcohol use
Analysis
Biology and Life Sciences
Body mass
Body mass index
Body size
Body weight loss
Cognition Disorders - physiopathology
Cognitive ability
Cohort Studies
Community colleges
Dementia
Diabetes
Diabetes mellitus
Disease
Disease prevention
Empirical analysis
Exercise
Female
Geriatrics
Health aspects
Health care
Health risk assessment
Humans
Impairment
Japan
Life Style
Lifestyles
Male
Mathematical analysis
Measurement
Medicine and Health Sciences
Middle age
Middle Aged
Middle schools
Nutrition
Older people
Physical activity
Physical therapy
Population
Preventive medicine
Public health
Regression analysis
Smoking
Social Sciences
Studies
Surveys
Systematic review
University graduates
Validity
Weight Loss
Young Adult
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Summary:Few empirical studies have been conducted to identify modifiable factors that may affect cognitive impairment in Japanese individuals. The present study aimed to clarify whether body mass and lifestyle are associated with cognitive impairment in Japanese middle-aged and elderly individuals. Subjects were 1814 community-dwelling individuals aged 44-79 years, all of whom were participants of the Murakami Cohort Study baseline survey conducted in 2011-2013. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) in 2014-2016, and cognitive impairment, the outcome measure, was defined as an MMSE score
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0185960