A single-center randomized controlled trial observing the safety and efficacy of modified step-up graded Valsalva manoeuver in patients with vasovagal syncope

Non-pharmacological therapies, especially the physical maneuvers, are viewed as important and promising strategies for reducing syncope recurrences in vasovagal syncope (VVS) patients. We observed the efficacy of a modified Valsalva maneuver (MVM) in VVS patients. 72 VVS patients with syncope histor...

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Bibliographic Details
Published in:PloS one 2018-01, Vol.13 (1), p.e0191880-e0191880
Main Authors: He, Li, Wang, Lan, Li, Lun, Liu, Xiaoyan, Yu, Yijun, Zeng, Xiaoyun, Li, Huanhuan, Gu, Ye
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Analysis
Blood pressure
Cardiac arrhythmia
Cardiology
Cardiovascular system
Female
Heart rate
Hemodynamics
Hospitals
Humans
Incidence
Intervals
Intervention
Male
Maneuvers
Medicine and Health Sciences
Middle Aged
Nervous system
Patients
Pharmacology
Quality of life
Research and Analysis Methods
Risk factors
Standard deviation
Syncope
Syncope, Vasovagal - physiopathology
Tilt-Table Test
Valsalva exercise
Valsalva Maneuver
Valsalva's maneuver
Vasovagal syncope
Young Adult
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Summary:Non-pharmacological therapies, especially the physical maneuvers, are viewed as important and promising strategies for reducing syncope recurrences in vasovagal syncope (VVS) patients. We observed the efficacy of a modified Valsalva maneuver (MVM) in VVS patients. 72 VVS patients with syncope history and positive head-up tilt table testing (HUTT) results were randomly divided into conventional treatment group (NVM group, n = 36) and conventional treatment plus standard MVM for 30 days group (MVM group, n = 36). Incidence of recurrent syncope after 12 months (6.5% vs. 41.2%, P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0191880