Barriers and facilitators to antiretroviral therapy adherence among Peruvian adolescents living with HIV: A qualitative study

AIDS deaths among adolescents are increasing globally. This qualitative study investigated the barriers and facilitators to cART adherence among Peruvian adolescents living with HIV. Guided by a social ecological model, we analyzed transcripts from 24 psychosocial support groups for HIV-positive ado...

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Bibliographic Details
Published in:PloS one 2018-02, Vol.13 (2), p.e0192791-e0192791
Main Authors: Galea, Jerome T, Wong, Milagros, Muñoz, Maribel, Valle, Emiliano, Leon, Segundo R, Díaz Perez, Dayana, Kolevic, Lenka, Franke, Molly
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adhesion
Adolescent
Adolescents
AIDS
Anti-HIV Agents - adverse effects
Anti-HIV Agents - economics
Anti-HIV Agents - therapeutic use
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Biology and Life Sciences
Caregivers
Dosage and administration
Drug Costs
Drug therapy
Drugs
Ecological models
Ecological monitoring
Ecology and Environmental Sciences
Emotions
Evaluation
Family
HIV
HIV infections
HIV Infections - drug therapy
HIV Infections - psychology
Human immunodeficiency virus
Humans
Interpersonal Relations
Medicine and Health Sciences
Mortality
Patient Compliance
Pediatrics
Peer Group
People and Places
Peru
Qualitative research
Side effects
Social Sciences
Social Support
Teenagers
Young adults
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Summary:AIDS deaths among adolescents are increasing globally. This qualitative study investigated the barriers and facilitators to cART adherence among Peruvian adolescents living with HIV. Guided by a social ecological model, we analyzed transcripts from 24 psychosocial support groups for HIV-positive adolescents aged 13-17 years and 15 individual, in-depth interviews with cART providers and caregivers to identify the barriers and facilitators to cART adherence at the individual, family/caregiver and hospital levels. Most barriers and facilitators to cART adherence clustered at the individual and family/caregiver levels, centering on support provided to adolescents; history of declining health due to suboptimal cART adherence; side effects from antiretroviral drugs; and cART misinformation. Interventions to support adolescent HIV cART adherence should begin at the individual and family/caregiver levels and include an educational component. No adolescent living with HIV should die from AIDS in an era of accessible cART.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0192791