Detection of human bocavirus in Saudi healthy blood donors

Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2018-02, Vol.13 (2), p.e0193594
Main Authors: Abdel-Moneim, Ahmed S, Mahfouz, Mohammad E, Zytouni, Dalia M
Format: Article
Language:English
Subjects:
Adult
Analysis
Biology and Life Sciences
Blood
Blood & organ donations
Blood donors
Blood Donors - statistics & numerical data
Blood products
Blood transfusion
Causes of
Children
Computer and Information Sciences
Deoxyribonucleic acid
DNA
DNA, Viral - blood
Female
Gene sequencing
Genotypes
Healthy Volunteers
HIV
Human bocavirus - genetics
Human bocavirus - isolation & purification
Human immunodeficiency virus
Humans
Immunodeficiency
Infections
Infectious diseases
Male
Medicine and Health Sciences
Middle Aged
Polymerase chain reaction
Prevention
Research and Analysis Methods
Respiratory diseases
Respiratory tract diseases
Risk factors
Saudi Arabia
Studies
Transfusion
Virology
Virus diseases
Viruses
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by polymerase chain reaction. The HBoV genotype of positive samples was determined using direct gene sequencing. Twenty-one out of the three hundred blood samples were found to be positive for HBoV. Sequence analysis of the positive samples revealed that all the strains were related to the HBoV-1 type with a low rate of variation among the detected sequences. It was concluded that there is a considerable risk of contracting HBoV from a blood transfusion from normal healthy individuals.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0193594