Silodosin versus tamsulosin for medical expulsive treatment of ureteral stones: A systematic review and meta-analysis

Silodosin, a recently introduced selective α-blocker, has a much higher selectivity for the α-1A receptor. The efficacy and safety of silodosin compared to tamsulosin in medical expulsive therapy (MET) are controversial. The objective of this study was to assess the efficacy and safety of silodosin...

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Bibliographic Details
Published in:PloS one 2018-08, Vol.13 (8), p.e0203035-e0203035
Main Authors: Hsu, Yuan-Pin, Hsu, Chin-Wang, Bai, Chyi-Huey, Cheng, Sheng-Wei, Chen, Kuan-Chou, Chen, Chiehfeng
Format: Article
Language:English
Subjects:
Analysis
Bias
Biology and Life Sciences
Clinical medicine
Comparative analysis
Confidence intervals
Dosage and administration
Drug therapy
Ejaculation
Expulsion
Health services
Hospitals
Incidence
Kidney stones
Lithotripsy
Medicine
Medicine and Health Sciences
Meta-analysis
Observational studies
Pain
Patients
People and places
Physical Sciences
Public health
Quality
Regression analysis
Research and Analysis Methods
Safety and security measures
Sensitivity analysis
Silodosin
Statistical analysis
Stone
Studies
Subgroups
Systematic review
Tamsulosin
Treatment outcome
Urology
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Summary:Silodosin, a recently introduced selective α-blocker, has a much higher selectivity for the α-1A receptor. The efficacy and safety of silodosin compared to tamsulosin in medical expulsive therapy (MET) are controversial. The objective of this study was to assess the efficacy and safety of silodosin compared to tamsulosin for treating ureteral stones
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0203035