Dosimetric superiority of IMRT with jaw tracking technique for whole esophagus and T-shaped field radiotherapy in advanced esophageal cancer

For whole esophagus and T-shaped field radiotherapy using intensity modulated radiotherapy (IMRT) technique in advanced esophageal cancer, lower absorbed doses to lung and heart remains a challenge. The aim of this study was to investigate the dosimetric superiority in IMRT plans with jaw tracking t...

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Bibliographic Details
Published in:PloS one 2018-09, Vol.13 (9), p.e0202628-e0202628
Main Authors: Shi, Liwan, Lai, Youqun, Chen, Shanyu, Fu, Lirong, Lin, Qin
Format: Article
Language:English
Subjects:
Biology and Life Sciences
Cancer
Cancer patients
Cancer therapies
Care and treatment
Esophageal cancer
Esophageal Neoplasms - diagnostic imaging
Esophageal Neoplasms - radiotherapy
Esophagus
Feasibility studies
Health aspects
Heart
Humans
Irradiation
Jaw
Lungs
Lymphatic system
Medicine and Health Sciences
Oncology
Organs at Risk - radiation effects
Patients
Planning
Radiation therapy
Radiometry
Radiotherapy
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Intensity-Modulated - adverse effects
Radiotherapy, Intensity-Modulated - instrumentation
Reduction
T shape
Time Factors
Tomography, X-Ray Computed
Tracking
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Summary:For whole esophagus and T-shaped field radiotherapy using intensity modulated radiotherapy (IMRT) technique in advanced esophageal cancer, lower absorbed doses to lung and heart remains a challenge. The aim of this study was to investigate the dosimetric superiority in IMRT plans with jaw tracking technique for whole esophagus radiotherapy. Thirty-two patients with esophageal cancer were subjected to IMRT treatment plans using Eclipse treatment planning system. For every patient, four different plans were generated with six gantry angles: six large fields IMRT plans with fixed jaw (6F-IMRT), six large fields IMRT plans with jaw tracking technique (6F-IMRT-T), twelve small fields IMRT plans with fixed jaw (12F-IMRT), and twelve small fields IMRT plans with jaw tracking technique (12F-IMRT-T). Dosimetric evaluation was assessed for all plans. For every technique, there were no differences in planning target volume (PTV) coverage and conformity. 6F-IMRT-T plans could significantly reduce lung irradiation with 7.9% (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0202628